ESMO Handbook of Interpreting Oncological Study Publications

2018 ESMO Handbook of Interpreting Oncological Study Publications cover

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Watch the video presenting the Handbook by Veronika Ballová , co-editor of the ESMO Handbook of Interpreting Oncological Study Publications and member of the ESMO Educational Publications Working Group

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ESMO members: You can now read this handbook on your iPad, tablet or Kindle! Download the .epub file for iPads and tablets or the .mobi file for Kindle. You will need to be logged in to your ESMO account to download the files.

.mobi .epub

In the past decade, the scientific world of oncology has changed considerably. An ever-increasing number of new interventions are being evaluated and study results are disseminated via an expanding number of peer-reviewed journals, congress presentations and other reports.

The ESMO Handbook of Interpreting Oncological Study Publications enables all of us to read between the lines of a scientific publication, to better estimate the true benefit of a new oncological intervention and to better understand other cancer-related research.

We take the clinician through studies that investigate the causes of cancer, its prognosis and treatment. Each chapter focuses on a specific type of study, its design and its value, providing examples to show how the studies are done and how their findings are reported. In this way, we can better find the balance between treatment need, treatment benefit and treatment hazard for our patients, and keep cancer care affordable.


Mike Clarke
Veronika Ballová
Henk van Halteren


Chapter 1 - Risk Factors

Chapter 2 - Screening

Chapter 3 - Prognosis

Chapter 4 - Cancer Registries 

Chapter 5 - Drug Development (Including Phase I Trials) 

Chapter 6 - Randomised Trials

Chapter 7 - Choice of Outcomes (Including Core Outcome Sets and Surrogate Outcomes)

Chapter 8 - Statistical Issues (Including Subgroups, Time-To-Event Analyses, Multiplicity)

Chapter 9 - Systematic Reviews: A Key to Support Evidence-Informed Decision Making

Chapter 10 - Clinical Research in Rare Cancers

Chapter 11 - How to Become a Researcher