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Overview of the physiology and pathophysiology of the skin reactions associated with multikinase inhibitor treatment

This section, ‘Background research’, provides information relating to the current understanding of the physiology and pathophysiology of the skin reactions associated with multikinase inhibitor treatment, and contains a regularly updated compilation of ongoing research efforts in the field.

Classification and Scoring

International standard diagnostic classification system for all general epidemiological and clinical uses as well as the terminology provided for the grading of skin toxicity Common Terminology Criteria for Adverse Events.

Pathophysiology

Structure of skin and hair follicles, the effects of multikinase inhibitors on the skin and their mechanism of action.

Mechanism of Multikinase Inhibitor Action

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