Abstract 2344
Background
The Economist Intelligence Unit takes a strategic approach to understand the impact of policy on lung cancer. Recommendations from our research, sponsored by MSD, will assist countries to improve systemic responses because outcomes remain poor and costs remain high despite scientific progress.
Methods
Our research centres on 13 countries: Austria, Belgium, Finland, France, Germany, Greece, Netherlands, Norway, Poland, Romania, Spain, Sweden, and the UK. Our literature review drew evidence from internationally-recognised sources and falls into 5 domains operationalised by 17 indicators assessing performance across the entire patient journey. After consultation with European experts, we populated our scorecard comparing policy and practice, examining service delivery, systems, access, financing and governance. Examination of preliminary findings in country workshops with clinicians, patient organisations and other key stakeholders enabled us to obtain nuanced information providing a clearer grasp on care than obtained from desk research alone.
Results
While patches of good practice exist, no country scores highly across all of our measurements. All but one country has a national cancer control plan: 75% are over five years old and do not incorporate recent oncological innovations. Clinical guidelines lack details on accelerating suspected lung cancer patients for diagnosis, referral pathways to secondary/tertiary care, supportive/palliative care, shared decision-making and psychological support within a specified time. Cancer registries exist in each country, yet clinicians report that clinically-focused cancer registries could house important information. Only 5 countries reimburse all four commonly used biomarkers for lung cancer.
Conclusions
Room for improvement in lung cancer policy exists across all the countries and domains we have studied. Our workshops ensured we focus on the most important opportunities for improving the delivery of lung cancer care relevant for each country. Now, based on the recommendations coming out of the research and agreed upon by stakeholders, we are in the policy development phase of our work where our goal is to assist policymakers improve care for people living with lung cancer in Europe.
Clinical trial identification
Editorial acknowledgement
Legal entity responsible for the study
The authors.
Funding
MSD.
Disclosure
All authors have declared no conflicts of interest.
Resources from the same session
2553 - Interim analysis of a phase Ib study of cobimetinib plus atezolizumab in patients with advanced BRAFV600 wild type melanoma progressing on prior anti-PD-L1 therapy
Presenter: Shahneen Sandhu
Session: Poster Display session 3
Resources:
Abstract
2743 - The Impact of Targeted Therapies and Immunotherapy in Melanoma Brain Metastases: a Systematic Review and Meta-Analysis
Presenter: Mario Mandala
Session: Poster Display session 3
Resources:
Abstract
5479 - Intracranial Anti-Tumor Activity in Melanoma Brain Metastases with Encorafenib Plus Binimetinib: A Multicenter, Retrospective Analysis
Presenter: Jose Lutzky
Session: Poster Display session 3
Resources:
Abstract
3560 - Outcomes of Patients with Melanoma Brain Metastases (MBM) Treated with Standard of Care Therapy After Being Excluded from MBM-Specific Clinical Trials
Presenter: Kourtney Holbrook
Session: Poster Display session 3
Resources:
Abstract
3175 - The analysis of current treatment outcomes in melanoma patients with brain metastases
Presenter: Joanna Placzke
Session: Poster Display session 3
Resources:
Abstract
4550 - A multivariate model to define prognostic groups among patients with melanoma brain metastases: a 10-year retrospective cohort study
Presenter: Giacomo Pelizzari
Session: Poster Display session 3
Resources:
Abstract
4191 - The immune landscape of melanoma significantly influences survival in patients with highly mutated tumors.
Presenter: Robert Ferguson
Session: Poster Display session 3
Resources:
Abstract
1625 - Final Results from Phase II of Combination with Canerpaturev (formerly HF10), an Oncolytic Viral Immunotherapy, and Ipilimumab in Unresectable or Metastatic Melanoma in 2nd-or later line treatment
Presenter: Kenji Yokota
Session: Poster Display session 3
Resources:
Abstract
5346 - Evaluating polygenic risk score prediction model for melanoma prognosis
Presenter: Miriam Potrony
Session: Poster Display session 3
Resources:
Abstract
5477 - Impact of sarcopenia in patients with metastatic melanoma treated with immunotherapy
Presenter: Maria Grazia Vitale
Session: Poster Display session 3
Resources:
Abstract