Episode 3: Skin Toxicity Induced by Targeted Therapy

Episode 3: Skin Toxicity Induced by Targeted Therapy  
Presented by Zoe Apalla, Greece

Dermatologist Zoe Apalla explores skin toxicities associated with targeted therapies, particularly EGFR and VEGF inhibitors. She discusses reactions such as acneiform rash, paronychia, xerosis, and PPE, outlining pre-emptive and reactive treatment strategies. Zoe emphasises prophylactic skincare and highlights collaboration between oncologists and dermatologists to ensure optimal patient care and treatment continuity.
Episode 3 Covers:

• Skin toxicities associated with targeted therapies, focusing on EGFR and VEGF inhibitors.
• Common dermatologic reactions, including acneiform rash, xerosis, paronychia, photosensitivity, nail changes, and Palmar-Plantar Erythrodysesthesia (PPE)
• Pre-emptive versus reactive strategies for managing papulopustular rash, highlighting prophylactic skincare, topical steroids, and systemic antibiotics.
• The importance of multidisciplinary collaboration between oncologists and dermatologists for early identification and effective management of skin toxicities.