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Episode 2: Dermatological Adverse Events of Systemic Cytotoxic Chemotherapy

Educational Mini-Series: Understanding Skin Toxicities in Cancer Therapy

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Episode 2: Dermatological Adverse Events of Systemic Cytotoxic Chemotherapy
Presented by Lidija Kandolf, Serbia

Dermatologist Lidija Kandolf examines skin toxicities linked to cytotoxic chemotherapy, focusing on common dermatological reactions such as hand-foot syndrome, alopecia, PATEO, and extravasation injury. She discusses hypersensitivity reactions related to taxane and platinum agents and provides practical strategies, including scalp cooling for alopecia, antidotes for extravasation, and skin testing protocols.
Episode 2 Covers:

  • Clinical manifestations and grading of dermatological reactions related to chemotherapy (e.g. hand-foot syndrome, PATEO, alopecia, and extravasation injury)
  • Mechanisms behind dermatological reactions and hypersensitivity caused by taxane and platinum agents
  • Practical management strategies including prevention and treatment of alopecia (scalp cooling), extravasation injury (antidotes), hypersensitivity reactions (skin testing and desensitisation), and dermatological adverse events (dose modifications, supportive care)

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