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ESMO22 Expert report on tackling resistance to CDK4/6 inhibitors in ER+/HER2-metastatic breast cancer

Shaheenah Dawood discusses abstracts from the ESMO Congress 2022:

- 210O - Mutational signature analysis reveals patterns of genomic instability linked to resistance to endocrine therapy (ET) +/- CDK 4/6 inhibition (CDK4/6i) in estrogen receptor-positive/HER2-negative (ER+/HER2-) metastatic breast cancer (MBC)
- LBA20: Open-label, randomized study of lasofoxifene (LAS) vs fulvestrant (Fulv) for women with locally advanced/metastatic ER+/HER2- breast cancer (mBC), an estrogen receptor 1 (ESR1) mutation, and disease progression on aromatase (AI) and cyclin-dependent kinase 4/6 (CDK4/6i) inhibitors

This video was supported with an unrestricted grant from Bayer Healthcare.
The study results covered, and the presenter of this expert video, have been selected exclusively by ESMO.

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