Oops, you're using an old version of your browser so some of the features on this page may not be displaying properly.

MINIMAL Requirements: Google Chrome 24+Mozilla Firefox 20+Internet Explorer 11Opera 15–18Apple Safari 7SeaMonkey 2.15-2.23

ESMO21 Expert Video Report on head and neck cancer

Reporting from the ESMO Congress 2021, Paolo Bossi provides an overview of important results related to the potential benefits of immunotherapy in head and neck cancer. First he discusses the results of the GORTEC-REACH trial in locally advanced SCCHN testing avelumab-cetuximab-radiotherapy, and the KEYNOTE-122 study in recurrent or metastatic nasopharyngeal carcinoma testing pembrolizumab.
He then explains the results of a retrospective analysis designed to identify the genomic profile determining the best response to immunotherapy. Among possible reasons for unconclusive results is the need for patients selection based on biomarkers. He also suggests a possible role of maintenance immunotherapy after radiotherapy.


  • LBA35 - Avelumab-cetuximab-radiotherapy versus standards of care in patients with locally advanced squamous cell carcinoma of head and neck (LA-SCCHN): first analysis of randomized phase III GORTEC-REACH trial - Prof Jean Bourhis, CH
  • 858O - Results of KEYNOTE-122: a phase 3 study of pembrolizumab (pembro) monotherapy vs chemotherapy (chemo) for platinum-pretreated, recurrent or metastatic (R/M) nasopharyngeal carcinoma (NPC) - Prof Anthony T.C. Chan, HK
  • 862MO - Gene expression profile differentiates short- and long-term survivors with immunotherapy in patients with recurrent/metastatic head and neck cancer - Dr Paolo Bossi, IT

This video was supported with educational grants from Novartis and Roche.
The study results covered, and the presenter of this expert video, have been selected exclusively by ESMO.

This site uses cookies. Some of these cookies are essential, while others help us improve your experience by providing insights into how the site is being used.

For more detailed information on the cookies we use, please check our Privacy Policy.

Customise settings
  • Necessary cookies enable core functionality. The website cannot function properly without these cookies, and you can only disable them by changing your browser preferences.