Abstract 157P
Background
Single-port video-assisted thoracoscopic surgery (SP VATS) is gaining popularity due to smaller and fewer incisions. While many studies highlight superior short-term surgical outcomes of SP VATS compared to conventional multi-port VATS (MP VATS), limited data exist regarding long-term oncological outcomes. This study evaluates the oncological feasibility of SP VATS by comparing long-term survival outcomes to MP VATS.
Methods
A retrospective cohort study was conducted involving 1,499 patients diagnosed with early-stage non-small cell lung cancer (NSCLC) who underwent SP VATS (749 patients) or MP VATS (750 patients) between January 2010 and October 2022. Propensity score matching was utilized to minimize baseline characteristic differences. Kaplan-Meier survival analysis and Cox proportional hazards models were used to compare overall survival (OS) and disease-free survival (DFS).
Results
Kaplan-Meier survival analysis revealed no significant difference in 5-year OS between SP VATS (82%) and MP VATS (83%) (P=0.17). Similarly, the 5-year DFS rates were comparable between the SP VATS and MP VATS groups (P=0.079). Multivariate analysis identified pathological T stage (HR: 1.6; 95% CI: 1.2–2.1; P < 0.01) and pathological N stage (HR: 2.4; 95% CI: 1.8–3.1; P < 0.01) as independent predictors of DFS. The surgical approach (SP VATS vs. MP VATS) was not a significant predictor of long-term outcomes in univariate or multivariate analyses.
Conclusions
SP VATS does not exhibit oncological inferiority to MP VATS. These findings support the feasibility of SP VATS as an effective and oncologically sound surgical approach for lung cancer, with comparable long-term survival outcomes.
Legal entity responsible for the study
The author.
Funding
Has not received any funding.
Disclosure
The author has declared no conflicts of interest.