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E-Poster Display

CN44 - Thrombosis in cancer patients related to central venous catheter

Date

17 Sep 2020

Session

E-Poster Display

Presenters

Angeles Benito-Yagüe

Citation

Annals of Oncology (2020) 31 (suppl_4): S1079-S1082. 10.1016/annonc/annonc318

Authors

A. Benito-Yagüe1, C. Garzón-Serrano1, I. de la Haba2, E. Coma2, R. Comabella2, M. Rodríguez2, R. Mestre2, P. Fernández-Ortega3

Author affiliations

  • 1 Chemotherapy Unit, ICO - Institut Català d'Oncologia l'Hospitalet (Hospital Duran i Reynals), 08013 - Barcelona/ES
  • 2 Emergency Unit, ICO - Institut Català d'Oncologia l'Hospitalet (Hospital Duran i Reynals), 08013 - Barcelona/ES
  • 3 Nursing Resarch, ICO - Institut Català d'Oncologia l'Hospitalet (Hospital Duran i Reynals), 08013 - Barcelona/ES

Resources

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Abstract CN44

Background

Use of central venous catheter CVC is increasingly common for cancer patients. It brought many benefits but also is associated with non-negligible risk of complications. Role of nurses is vital; they participate on indication, placement and maintenance of catheters. Trained nurses detect early identification of alarm signs/symptoms for rapid diagnosis and initiation of the most appropriate treatment.

Objective: to describe nursing activity in the clinics of chemotherapy unit in the care of patients with suspected deep venous DVT, in patients with a central venous catheter (CVC).

Methods

Descriptive cross-sectional study along one year 2019. Patients receiving treatment at 3rd level cancer centre chemotherapy. Data was descriptive analysed.

Results

Of 1039 central catheters, 467 were portal and 572 Peripheral Insertion Central catheters. 31 cases of venous thromboembolism (VTE); 4.02% in Peripheral vs 1.71% in portal, (p=.046). Mean age of 60years-old (32-86). Location in right side 71%; 74% Basilica and 26% in Subclavii. Most catheters, 97% only one lumen. Type of tumour: Breast 29%, lung 16%, colorectal 13%. Half of them localized disease and receiving adjuvant chemotherapy 64%. Drugs were cisplatin 23% and fluorouracil 17%, taxol 16% and vinorelbin 10%. Regarding first sign of thrombosis was oedema 94%, erythema 17%, pain 58% and collateral venous in 5%.

D-dimer blood test mean was 911 (319-2588). The follow-up was 218 days (50-363). 94% of patients were treated with low molecular weight heparin (LMWH) at therapeutic dosages. Complications: 1 case infection and 81% extensive thrombosis. One patient had minor bleeding related to heparin and 6% had re-thrombosis. 86% completed anticoagulant treatment, average length was 142.6 days (28-348), 14% did not (1 case death past 50 days, one patient decision and one per other decisions).

Conclusions

The incidence of thrombosis is higher in PICCS compared to PACS, predominantly right and catheter was preserved in most cases to continue chemotherapy.

- Nursing, that monitories during chemotherapy closely to patients are essential to detect thrombosis and to initiate early treatment, prevent complications that permit to finish chemotherapy with same catheter.

Clinical trial identification

Editorial acknowledgement

Legal entity responsible for the study

Angeles Benito.

Funding

Has not received any funding.

Disclosure

All authors have declared no conflicts of interest.

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