Abstract 513P
Background
The geriatric screening tool was developed to identify fit elderly cancer patients who could receive standart treatment from those who would benefit from a comprehensive geriatric assessment to guide the best treatment. The present study aimed to evaluate the role of the G8 screening tool in predicting overall survival in elderly colon cancer patients.
Methods
Between January 2016 and December 2018, geriatric screening tools was performed on consecutive patients aged > 75 years diagnosed with colon cancer at the Catalan Oncology of Institute. The assessment includes social status, functionality (activities of daily living, ECOG), cognition and G8. The G8 scale was classified into three groups according to their G8 score: >14 as the high score group, 11-14 as the intermediate score group, and <11 as the low score group.
Results
Out of 245 enrolled patients, 45% were classified as stage IV, of which 38% were women. Median age of these patients was 80 years (range 75-87). ECOG was 0-1 in 160 patients and 2 or more in 74. Among all patients, the low score group, with a median OS of 16 months survived significantly less than the high score group with a median OS of 34,1 months (p=0.001). In metastasic patients, median OS was 7,2 months in the low score group, and 30,3 months in the high score group. The difference was statistically significant (p=0.001). When patients with an ECOG of 2 or 3 were analized, patients with a lower G8 score showed shorter OS than patients with a higher score.
Conclusions
The G8 score helps identify patients with poor prognosis and improved the ECOG’s prognostic value. The G8 can help physicians make about the treatment decisions of advanced colon cancer in elderly patients.
Clinical trial identification
Editorial acknowledgement
Legal entity responsible for the study
Gemma Soler.
Funding
Has not received any funding.
Disclosure
All authors have declared no conflicts of interest.