Oops, you're using an old version of your browser so some of the features on this page may not be displaying properly.

MINIMAL Requirements: Google Chrome 24+Mozilla Firefox 20+Internet Explorer 11Opera 15–18Apple Safari 7SeaMonkey 2.15-2.23

E-Poster Display

1788P - Persistent sex-differences in lung cancer mortality between 2001 and 2017 in the US and EU

Date

17 Sep 2020

Session

E-Poster Display

Topics

Tumour Site

Small Cell Lung Cancer

Presenters

Chinmay Jani

Citation

Annals of Oncology (2020) 31 (suppl_4): S974-S987. 10.1016/annonc/annonc290

Authors

C.T. Jani1, D.C. Marshall2, R. Goodall3, H. Singh4, J. Shalhoub5, J. Salciccioli6, C.C. Thomson7

Author affiliations

  • 1 Internal Medicine, Mount Auburn Hospital - Harvard Medical School, 02138 - Cambridge/US
  • 2 Department Of Clinical Neurosciences, University of Oxford, Oxford/GB
  • 3 Department Of Surgery, Imperial College of London, London/GB
  • 4 Pulmonary And Critical Care, Medical College of Wisconsin, Froedtert Hospital, Milwaukee/US
  • 5 Department Of Vascular Surgery, Imperial College of London, W21NY - London/GB
  • 6 Internal Medicine, Mount Auburn Hospital - Harvard Medical School, 02163 - Cambridge/US
  • 7 Department Of Medicine - Division Of Pulmonary And Critical Care, Mount Auburn Hospital - Harvard Medical School, Cambridge/US

Resources

Login to get immediate access to this content.

If you do not have an ESMO account, please create one for free.

Abstract 1788P

Background

The lung is the most common site of cancer and has the highest worldwide cancer-related mortality. Advancements in lung cancer screening, new therapeutics, and guideline driven care over the past two decades have resulted in improvements in mortality. Few studies have reported on lung cancer trends in the 21st century. This study assessed the difference between lung cancer mortality by gender in the United States (US) and European Union (EU).

Methods

We utilized the World Health Organization (WHO) Mortality Database for European mortality data and Center for Disease Control (CDC) Wonder database for US mortality data. We extracted lung cancer mortality data from 2000 to 2017 based on ICD 10 system. Crude mortality rates were dichotomized by sex and reported by year. We computed Age Standardized Death Rates (ASDRs) per 100,000 population using the World Standard Population (and USA standard population for CDC mortality). We computed the ratio of male to female mortality over the observation period.

Results

We analyzed data from a total of 26 EU countries and the US, of which 6 countries had data till 2017, 12 till 2016, 7 till 2015 and 2 till 2014. All countries had greater mortality in men compared to women in all years. All countries had an overall decrease in the ratio of male-to-female mortality over the observation period. Specifically, in 2000, the median male-to-female mortality was 5.35 (IQR 3.65, 6.06) and for the most recent observation the median male-to-female mortality ratio was 2.26 (1.92, 4.05). The countries with the greatest current disparity in lung cancer mortality were Lithuania (5.51), Latvia (5.00), and Bulgaria (4.4). The countries with the smallest difference in mortality between sexes were Sweden (1.1), Denmark (1.13), United Kingdom (1.39). The median percentage change for all countries was – 44.45 (-50.44, - 30.56). The countries with the greatest percentage change were Spain (- 55.19), Belgium (-55.18), Cyprus (-53.64). The countries with the smallest percentage change were Bulgaria (-21.65), USA (-22.05), and Portugal (-25.46).

Conclusions

This study reports a decrease in the ratio of male-to-female mortality over the observation period across the EU and US. The greatest sex differences in mortality were in Eastern European countries and the smallest differences were in Northern Europe.

Clinical trial identification

Editorial acknowledgement

Legal entity responsible for the study

The authors.

Funding

Has not received any funding.

Disclosure

All authors have declared no conflicts of interest.

This site uses cookies. Some of these cookies are essential, while others help us improve your experience by providing insights into how the site is being used.

For more detailed information on the cookies we use, please check our Privacy Policy.

Customise settings
  • Necessary cookies enable core functionality. The website cannot function properly without these cookies, and you can only disable them by changing your browser preferences.