Abstract 971P
Background
Orbit is an uncommon location for malignant tumors, whether, primary or secondary. When exists, a personalized treatment strategy is warranted for these rare cases. In this study, we highlighted the most prominent clinical, pathological and survival properties of patients with orbital malignancies diagnosed at the united states from 1990 to 2016, using the SEER data base.
Methods
The study was conducted through SEER* Stat version 8.3.6. Data about patients having orbital tumors were obtained from SEER Reg Nov 2019, then were statistically analyzed using SPSS version 22.
Results
At the period from 1990 till 2016, 15036 patients were found to have orbital malignancies, of whom, male gender was more common than female one (n= 8235, 54.8%). The mean age at diagnosis was 54.9 years. Incidence rate of orbital tumors was estimated to be 8.6 per 1,000,000. Left sided orbit was more likely to be inhabited by the tumor, than the right side (n=7203, 47.9%). Malignant melanoma was the most frequent histology detected within the orbit (n= 7994, 53.2%), and surgery was performed for the vast majority of cases (n= 7775, 51.7%). The tumor was the only primary malignancy confirmed (n= 11191, 74.4%). The median survival was 62 months, with relative and observed survival at 5 years were 83.8% & 75.5, respectively.
Conclusions
Orbital tumors are, relatively, uncommon tumors, with incidence rate is about 8.6 per million. Malignant melanoma tends to be the most frequent pathology diagnosed among all orbital malignancies. Survival is, to some extent, long, with observed survival at 5 years is estimated to be 75.5%.
Clinical trial identification
Editorial acknowledgement
Legal entity responsible for the study
The author.
Funding
Has not received any funding.
Disclosure
The author has declared no conflicts of interest.