Abstract 1557P
Background
Acinar cell carcinomas are rare tumors, which constitute about 4% of the whole pancreatic tumors. Consequently, little data, about their clinical and survival characteristics are available. In this study, we demonstrate the clinico- epidemiological properties of patients with pancreatic acinar cell carcinoma in the united states between 1990 and 2015.
Methods
The study was conducted through SEER* Stat version 8.3.6. Data about pancreatic acinar cell carcinoma were obtained from SEER Reg Nov 2019, then these data were statistically analyzed using SPSS version 22.
Results
A total number of 447 patients with pancreatic acinar cell carcinoma were diagnosed at the period from 1990 till 2015. The incidence rate of pancreatic acinar cell Carcinoma was 0.25 per 1,000,000. Male patients represented 69.8% of patients, with the mean age at diagnosis 64.5 years. The majority of the tumors occupied the head of pancreas (n=193, 43.25%). 44%of patients had metastatic disease at presentation and only 49% of patients underwent primary pancreatic surgery. The tumor was the only primary malignancy diagnosed in the vast majority of cases (n= 362,81.5%). The median survival was 13 months.
Conclusions
Pancreatic acinar cell carcinoma is, quiet, uncommon tumor, with the incidence rate is estimated to be of 0.25 per 1,000,000. Most of the tumors were metastatic at presentaion, with a short median survival (13 months).
Clinical trial identification
Editorial acknowledgement
Legal entity responsible for the study
Belal Abousaida.
Funding
Has not received any funding.
Disclosure
All authors have declared no conflicts of interest.