Abstract 70P
Background
As life expectancy increases, the number of elderly patients with soft-tissue sarcoma (STS), for whom aggressive surgery may not be indicated due to poor general condition, is expected to increase. The purpose of this study is to evaluate the prognosis of >70 years old patients with STS who did not undergo surgery and reasons for non-surgical management.
Methods
>70 years old patients with STS and treated without surgery between 2013 and 2023 at our institution were included. Age, sex, follow-up period, tumor size, histopathological diagnosis, tumor location, tumor depth, performance status (PS), and reason for non-surgical management were reviewed. In addition, sarcoma-specific survival (SSS) was calculated.
Results
Out of 94 patients with STS, of whom each medical chart was reviewed, 11 patients did not undergo surgery. The median age was 84 years (range 72–95). Patients consisted of 6 male and 5 female. The median follow-up period was 5.1 months (range 1.1–34.2). Tumor size was over 10 cm in all patients. All patients were diagnosed by histopathological examination as follows: 2 patients of liposarcoma, 1 patient of each undifferentiated pleomorphic sarcoma (UPS), Ewing sarcoma, leiomyosarcoma. 6 patients were diagnosed as STS, of which specific type could not be confirmed. The tumors were located in the lower extremities in 5 patients and the trunk in 6 patients. The depth of the tumors was as follows: deeper than the superficial fascia in 10 patients and shallower than the superficial fascia in 1 patient. The PS was as follows: 0 in 1 patient, 1 in 6 patients, 2 in 2 patients, 3 in 1 patient, 4 in 1 patient. Two patients rejected indicated surgeries. In other 9 patients, surgeries were not indicated due to the following reasons: 7 patients had distant metastases, 1 patient was in poor general condition, 1 patient was considered inoperable because the tumor was located deep in the axilla. The 1-year SSS was 20%.
Conclusions
Even in >70 years old elderly patients with STS, the most primary reason for non-surgical management was the presence of metastases, although neither age nor poor general condition.
Clinical trial identification
Editorial acknowledgement
Legal entity responsible for the study
The authors.
Funding
Has not received any funding.
Disclosure
All authors have declared no conflicts of interest.