Abstract 57P
Background
Amongst gynaecological cancers, ovarian cancers are associated with unfavourable prognosis and high mortality owing to presentation at advanced stages. Present study aims to compare two diagnostic algorithms, International Ovarian Tumor Analysis (IOTA) Simple Ultrasound Rules versus Risk of Malignancy Index (RMI 2) for detection of ovarian malignancies.
Methods
50 consenting patients with ovarian mass (reproductive and menopausal age groups) evaluated at our institute over a period of nine months were prospectively enrolled. Patients were subjected to detailed examination, ultrasonographic assessment by gynaecologists and lab investigations including CA 125 was done. Data was collected using a standardised pretested proforma. Patient management as per departmental protocol was continued.
Results
IOTA Simple Ultrasound Rules consistently performed better than RMI 2 in detection of ovarian malignancies, with better sensitivity (96.96% vs 75.6%), specificity (71.4% vs 64.7%), positive predictive value (88.8% vs 80.6%) and negative predictive value (90.9% vs 57.8%) respectively.
Conclusions
Results of present study indicates that IOTA Simple USG Rules has better Sensitivity, Specificity, Positive Predictive Value and Negative Predictive Value than Risk of Malignancy Index, and a larger study may be warranted to obtain results which can be extrapolated to the general population.
Legal entity responsible for the study
The authors.
Funding
Has not received any funding.
Disclosure
All authors have declared no conflicts of interest.