Abstract 1488P
Background
Patients with advanced cancer often experience distressing symptoms between appointments, leading to unplanned admissions and emergency room visits. The SUPPORT+ mobile app was developed to improve symptom monitoring and clinical support for these patients. This study aims to assess the feasibility and acceptability of the SUPPORT+ mobile app for monitoring symptoms and providing interventions in advanced cancer patients.
Methods
Patients in palliative care downloaded the app and used it for symptom monitoring weekly with remote advice from palliative nurses for 16 weeks. Feasibility was assessed based on app usage and retention rates. Outcomes were compared at baseline and week 16.
Results
Out of 109 participants (55.1% male, median age 68.7 years), 84 completed the study. During the study period, 16 patients passed away. Among the remaining participants, 76 actively used the SUPPORT+ app for weekly symptom reporting, receiving remote support from palliative nurses. The retention rate was 81.7%. Home exercise and cancer myths were the most accessed app domains. Comparing baseline and week 16 data, a significant increase was observed in completion of advanced directive (AD) (11.0% vs. 14.1%, p=0.046) and discussion on the preferred place of dying (27.3% vs. 32.1%, p=0.041). Furthermore, anxiety scale scores significantly decreased in week 16 compared to baseline (mean 6.5 vs. 5.7, p=0.024). There were no significant differences in emergency room visits, depression scale scores, or palliative care knowledge between baseline and week 16. Most participants (92.8%) reported the app as easy to use, indicating a high level of acceptance and usability. Additionally, 71.1% mentioned that the app positively influenced their health habits.
Conclusions
The SUPPORT+ app demonstrated feasibility and acceptability in facilitating end-of-life communication, increasing AD completion, and potentially reducing anxiety in advanced cancer patients. Further research is needed to explore its long-term efficacy in larger randomized controlled trials.
Clinical trial identification
Editorial acknowledgement
Legal entity responsible for the study
The authors.
Funding
Has not received any funding.
Disclosure
All authors have declared no conflicts of interest.
Resources from the same session
1607P - Association of the lipid biomarker, PCPro, and clinical outcomes in the ENZAMET trial (ANZUP 1304)
Presenter: Lisa Horvath
Session: Poster session 10
1608P - Prostate cancer working group 4 (PCWG4) preliminary criteria using serial PSMA PET/CT for response evaluation: Analysis from the PRINCE trial
Presenter: Michael Hofman
Session: Poster session 10
1609P - PSMA-PET and PROMISE re-define stage and risk in patients with prostate cancer
Presenter: Wolfgang Fendler
Session: Poster session 10
1610P - Circulating tumour cell (CTC) enumeration and overall survival (OS) in men with metastatic castration-resistant prostate cancer (mCRPC) treated with xaluritamig
Presenter: Andrew Armstrong
Session: Poster session 10
1611P - Haematologic impact of [177Lu]Lu-PSMA-617 versus ARPI change in patients with metastatic castration-resistant prostate cancer in PSMAfore
Presenter: Kim Nguyen Chi
Session: Poster session 10
1612P - Impact of FANCA, ATM, CDK12 alterations on survival in metastatic castration-resistant prostate cancer (mCRPC)
Presenter: David Lorente
Session: Poster session 10
1613P - Clinically advanced prostate cancer (CAPC) featuring BRCA2 loss: A comprehensive genomic profiling (CGP) study
Presenter: Chiara Mercinelli
Session: Poster session 10
1614P - PSA responses and PSMA scan changes after immunotherapy for biochemically recurrent prostate cancer (BCR) without androgen deprivation therapy (ADT)
Presenter: Ravi Madan
Session: Poster session 10
1615P - A new prognostic model of overall survival (OS) in patients (pts) with metastatic hormone sensitive prostate cancer (mHSPC)
Presenter: Susan Halabi
Session: Poster session 10