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Poster session 10

1502P - Sexual dysfunction and quality of life in rectal cancer

Date

14 Sep 2024

Session

Poster session 10

Topics

Cancer Treatment in Patients with Comorbidities;  Supportive and Palliative Care

Tumour Site

Presenters

Fatih Kus

Citation

Annals of Oncology (2024) 35 (suppl_2): S913-S922. 10.1016/annonc/annonc1604

Authors

F. Kus1, H.C. Yildirim2, D.C. Guven3, E. Chalabiyev4, F. sirvan5, O. Dizdar6, S. Yalcin7

Author affiliations

  • 1 Oncology Department, Hacettepe University - Faculty of Medicine, 06100 - Ankara/TR
  • 2 Oncology Department, Hacettepe University Oncology Hospital, 06230 - Ankara/TR
  • 3 Department Of Medical Oncology, Hacettepe University Oncology Hospital, 06230 - Ankara/TR
  • 4 Medical Oncology, Hacettepe University Oncology Hospital, 06230 - Ankara/TR
  • 5 Department Of Medical Oncology, Hacettepe University Medical School, 06100 - Ankara/TR
  • 6 Preventive Oncology Dept, Hacettepe University - Faculty of Medicine, 06100 - Ankara/TR
  • 7 Medical Oncology, Hacettepe University - Faculty of Medicine, 06100 - Ankara/TR

Resources

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Abstract 1502P

Background

Rectal cancer treatments have improved significantly over the past two decades, leading to higher survival rates. However, there's a growing emphasis on the long-term quality of life for survivors, including addressing sexual health needs. Our study aims to evaluate QOL, particularly sexual dysfunction, using validated tools like EORTC QLQ-C30, QLQ-CR29, and GRISS, aiming to improve care for rectal cancer patients.

Methods

Validated questionnaires (EORTC QLQ-C30, QLQ-CR29, GRISS) were completed by participants, assessing various aspects of quality of life and sexual satisfaction. Statistical analyses included tests for normality, descriptive analyses of patient characteristics, correlation analyses between questionnaire scores, and comparison of median scores using appropriate tests.

Results

The study included a total of 83 participants. Mean age of 55.95 ± 11.53, predominantly under 65 years (79.5%). A majority of patients (65.1%) had a stoma, and 78.3% underwent surgery, with 67.5% retaining sphincter function. The cohort was divided into non-metastatic (60.2%) and metastatic (39.8%) groups Significant correlations were observed between the Golombok Total Score and various subscores of the C30 scale. The fatigue subscore correlated positively with Golombok-female Total Score (r=0.331, p=0.041) and Golombok-male Total Score (r=0.370, p=0.042). Body image (p

Conclusions

This study demonstrates the profound and varied impact of rectal cancer treatment on patients' sexual health and overall quality of life, particularly affected by the presence of a stoma and metastatic disease.

Clinical trial identification

Editorial acknowledgement

Legal entity responsible for the study

The authors.

Funding

Has not received any funding.

Disclosure

All authors have declared no conflicts of interest.

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