Abstract 1639P
Background
In psychology, self-efficacy is the belief in one's own ability to manage a specific situation. Patients (pts) diagnosed with prostate cancer (PC) can have long and varied treatment pathways. Challenges include complex treatment options, limited healthcare resources, digitalization, and higher expectations of self-responsibility. We report from a digital survey that assessed self-efficacy in pts with PC in the UK.
Methods
A voluntary, anonymous, online survey aimed at pts with PC in the UK was conducted between 31 Jul and 11 Sep 2023. Awareness was generated primarily through social media advertisements. Pts were asked about their medical history, health-related quality of life (HRQoL), digital tool use, and involvement in shared decision-making. Self-efficacy was measured using the Cancer Survivor Self-Efficacy Scale and Cancer Behaviour Inventory-Brief Version (optional). Correlation analysis was by Spearman's rank correlation coefficient (Python).
Results
Completed surveys were received from 2463 pts with PC (median age 69 years) of whom 13% had metastasized disease. 50% of pts were college/university educated and 70% were aware of their Gleason score. ≥5 medications per day were taken by 46% of pts and <41% had used a type of digital tool to help manage their condition. FACT-P total score provided the strongest correlation to self-efficacy (Table). Self-efficacy was also positively correlated with shared decision-making, and satisfaction with digital tool use to engage with HCPs and aid self management. No correlation was observed for level of education, type of hospital (NHS, private, university), or age.Table: 1639P
Correlation with self-efficacy | Disease stage | Sample size | Correlation co-efficient |
Positive | |||
HRQoL assessed by FACT-P total score | All Met | 2463 326 | 0.785 0.761 |
Actively involved in shared decision making | All Met | 2409 324 | 0.346 0.288 |
Digital tool: ad-hoc reporting of medical issues to my care team | All Met | 609 105 | 0.412 0.414 |
Digital tool: Scheduled tele-consultation | All Met | 931 169 | 0.376 0.324 |
Digital tool: Scheduled remote care | All Met | 1002 154 | 0.361 0.420 |
FACT-P, Functional Assessment of Cancer Therapy Prostate Cancer questionnaire; HRQoL, health-related quality of life; Met, metastatic
Conclusions
In our survey in patients with PC and metastatic PC, a higher HRQoL was strongly related to higher self-efficacy levels. Shared decision-making and digital support tools also contributed to self-efficacy. These factors are within the remit of the patients' clinician/organization; their further use and the impact on self-efficacy should be evaluated systematically.
Clinical trial identification
Editorial acknowledgement
Medical writing assistance was provided by Martin Goulding, DPhil, from Mudskipper Business Ltd., funded by AstraZeneca.
Legal entity responsible for the study
AstraZeneca.
Funding
AstraZeneca.
Disclosure
J.M. O'Sullivan: Financial Interests, Personal, Invited Speaker: Astellas, Bayer, AAA/Novartis, Monrol, Sanofi, Imedica; Financial Interests, Personal, Advisory Board: AAA/Novartis, AstraZeneca, Janssen. N. Yeh, M. Chatterjee, S. Le Mare, A. Bettin: Financial Interests, Personal, Full or part-time Employment: AstraZeneca; Financial Interests, Personal, Stocks or ownership: AstraZeneca. R. Lehmann: Financial Interests, Personal, Officer, Founder and CEO: DontBePatient Intelligence; Financial Interests, Institutional, Research Grant, Founding of the Prostate Cancer Patient Survey: Novartis/AAA; Financial Interests, Institutional, Funding, Founding of Research Activities: AstraZeneca. All other authors have declared no conflicts of interest.
Resources from the same session
1658TiP - The STAMPEDE2 177Lutetium-PSMA-617 (177Lu-PSMA-617) trial: A phase III, randomised, open-label trial in patients with metastatic prostate cancer (mPC) starting androgen deprivation therapy (ADT)
Presenter: Minal Padden-Modi
Session: Poster session 11
1659TiP - A phase I, first-in-human, open-label, multicenter, trial-in-progress of the safety, tolerability, and preliminary efficacy of JNJ-87189401 (PSMA-CD28 bispecific antibody) combined with JNJ-78278343 (KLK2-CD3 bispecific antibody) for advanced prostate cancer
Presenter: Mark Stein
Session: Poster session 11
1660TiP - First-in-human study of ABBV-969, a dual variable antibody-drug conjugate (ADC), in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC)
Presenter: Raanan Berger
Session: Poster session 11
1661TiP - SEGNO: An exploratory study of the safety and efficacy of genomic biomarker-guided neoadjuvant therapy for locally advanced and oligometastatic prostate cancer
Presenter: Haichao Huang
Session: Poster session 11
1662TiP - HARMONY: A phase II study of niraparib (N)/abiraterone acetate (AA) plus prednisone (P) for Hispanic/Latino (HL) and non-Hispanic Black (NHB) patients (pts) with metastatic hormone sensitive prostate cancer (mHSPC) and deleterious homologous recombination repair alterations (HRRa)
Presenter: Qian Qin
Session: Poster session 11
1664P - Early integration of psycho-oncology in cancer care: A model of care from a quaternary care government hospital in India and its patient related outcomes
Presenter: Niharika Bisht
Session: Poster session 11
1665P - Awareness of illness, psychological difficulties, and resources across life ages in early stage and metastatic cancer patients
Presenter: Raffaela Sartori
Session: Poster session 11
1666P - Impact of substance use and mental health disorders on cancer care in urban underserved communities
Presenter: Eunhee Choi
Session: Poster session 11