CN86 - Review of nursing interventions for the management of psychosocial problems in adults after hematopoietic stem cell transplantation: A systematic review

Background

Psychosocial needs and problems after hematopoietic stem cell transplantation are very diverse, and survivors experience stress, fear of recurrence, anxiety and depression. It is reported that psychological problems that occur in patients reduce the quality of life and psychological well-being, and increase morbidity and mortality. However, no guideline includes interventions that can be applied in nursing care.This review aims to examine the effectiveness of nurse interventions for post-transplant psychosocial problems in adult patients undergoing hematopoietic stem cell transplantation.

Methods

In this review, we investigated studies from PubMed, Cochrane Library, Scopus, CINAHL, Web of Science and PsycINFO (all via Ovid SP) databases that met inclusion criteria. We also assessed the studies' methodological quality with the Cochrane and JBI checklists. This study was performed based on the Guidelines of Systematic Reporting of Examination presented in the PRISMA checklist.

Results

A total of nine published studies out of 102 studies were included in this review. All studies included in the study are randomized controlled trials. Of the nine studies, 4 were from the U.S., the others were from the U.K., the Netherlands, China, Switzerland, and Denmark. Psychosocial problems addressed in the post-transplant period were anxiety, depression, distress, and irritability. Multimodal intervention (exercise, progressive relaxation, and psychoeducation) (n=5), web-based intervention (n=3) and music therapy studies (n=1) were the preferred methods in nursing interventions.

Conclusions

Studies have reported an increase in depression, anxiety, and stress rates and a decrease in psychosocial health, quality of life, and well-being in patients undergoing hematopoietic stem cell transplantation in the post-transplant period. In addition, although research on nursing interventions for post-transplant psychosocial problems is limited, it is suggested that nursing interventions are effective in preventing and managing patients' psychosocial problems. In this context, larger observational studies should be conducted and the impact of nursing care should be investigated.

Clinical trial identification

PROSPERO International Prospective Register of Systematic Reviews System: CRD42023486753.

Editorial acknowledgement

Not applicable.

Legal entity responsible for the study

The authors.

Funding

Has not received any funding.

Disclosure

All authors have declared no conflicts of interest.