Abstract 2069P
Background
We previously reported the impairment of quality of life (QOL) of caregivers of patients with cancer (ann. oncol. 2019, vol.30 supple 9, IX142). A multifaceted longitudinal survey is warranted to establish a valid support system.
Methods
This single-institution prospective cohort study was conducted with the approval of the ethical committee of Ina Central Hospital. 48 pairs of patients with incurable cancer and their caregivers filled out questionnaires according to the Japanese version of EORTC QLQ C-30 before the initial session of the first and the second-line treatment. Patients: 31 men and 17 women with an average age of 68.3±10.6 years. Caregivers: 17 men and 31 women with an average age of 63.5±11.6 years. Primary sites of cancer: gastrointestinal system in 41 patients, lung in 4, head and soft tissue in 2 and neck in 1. Average duration of treatment: 228 ± 171 days, median 161 days. The influence of the treatment outcome (“responder with RECIST PR and CR” or “non-responder with SD and PD”) and duration (“shorter than 161 days” or “longer”) on the scales were investigated statistically.
Results
All the nine symptomatic scales of EORTC QLQ-C30 were positive in around 20% in caregivers before treatment. After treatment, fatigue (88%), pain (42%), and financial concerns (43%) scales changed more frequently. The emotional function (EF) and cognitive function (CF) scales showed no significant differences in patients and caregivers before and after treatment, unlike other comprehensive scales. The scale declined in 38% of caregivers in physical function, 15% in role function, 33% in emotional function, 28% in cognitive function, 33% in social function, 29% in global health, and 42% in summary score. EF and CF decreased by almost the same proportion in patients and caregivers. The duration and outcome of treatment did not have a correlation with changes in the scales of caregivers.
Conclusions
Consistent insufficiency of emotional and cognitive function in caregivers, similar to that in patients, was revealed throughout the treatment. The outcome and duration of treatment did not affect the caregivers’ mental condition. Caregivers of patients with cancer require emotional and cognitive function support throughout the patients’ treatment.
Clinical trial identification
Editorial acknowledgement
Vikas Narang.
Legal entity responsible for the study
N. Takeuchi.
Funding
Has not received any funding.
Disclosure
All authors have declared no conflicts of interest.
Resources from the same session
2116P - Preoperative body mass index, waist circumference, and mortality after major cancer surgery: A nationwide cohort study in South Korea
Presenter: Jiwon Yoon
Session: Poster session 06
2117P - Dietary patterns and clinical outcomes in patients with lung cancer: What needs to change
Presenter: Imanuely Borchardt
Session: Poster session 06
2118P - Refeeding syndrome: A prospective analysis in adults admitted to an oncology hospital
Presenter: Filipe Gonçalves
Session: Poster session 06
2119P - The prognostic impact of nutritional assessment and scores in advanced gastric cancer
Presenter: Sara Torresan
Session: Poster session 06
2120P - Nutritional deficiency post gastric cancer surgery
Presenter: Abay Makishev
Session: Poster session 06
2121P - Association between nutritional status and adverse events in gastrointestinal cancer patients undergoing outpatient chemotherapy in Japan
Presenter: Naoko Sato
Session: Poster session 06
2122P - Clinical significance of oncology patients’ nutritional status assessment
Presenter: Efthymios Kostaridis
Session: Poster session 06
2123P - Value of immuno-nutritional scores in the prognosis of hospitalised patients with lung cancer
Presenter: Jesús López
Session: Poster session 06
2124P - The impact of NUTRItional status at first medical oncology visit ON Clinical Outcomes: The NUTRIONCO study
Presenter: Maurizio Muscaritoli
Session: Poster session 06
2125P - Potential ROle of hypoVItaminosis D in patiENts with cancer treated with immune ChEckpoint inhibitors (PROVIDENCE): A prospective observational study
Presenter: Alessio Cortellini
Session: Poster session 06