2056P - Hospitalization, reconsultations and mortality in the field of oncological emergencies: Who is at higher risk?

Background

The wider availability of oncological treatment and the improved survival of cancer patients have increased the frequency of emergency consultations and their impact on healthcare. The aim of this study was to investigate the variables that influence hospital admission, re-consultation and clinical outcomes among oncology patients who seek emergency care.

Methods

Single-center, observational and prospective study. We analyzed a sample of 554 oncology patients who consulted in the Emergency Deparment during regular office hours between March-22 and March-23. Statistics: Chi-squared test to assess association between variables. Kaplan-Meier curves and log-rank test for survival analysis. Significance level: p-value <=0.05.

Results

The baseline characteristics of the study participants were: 50.2% females, 21.5% lung cancer, 68.8% stage IV, 25.8% consulted for digestive symptoms, 37% were hospitalized and 16.4% reconsulted in the following 15 days. The overall median survival was 54 weeks. Factors that were associated with a higher likelihood of hospitalization were lung cancer (26.9% of admissions), stage IV (80.7%), monotherapy chemotherapy (CT) (36.3%), first-line treatment for metastatic disease (40.9%), ECOG 2 (36.8%), digestive symptoms as reason for consultation (29.2%) and complications secondary to the tumor itself as definitive diagnosis (32.2%). Factors significantly associated with a higher likelihood of reconsultation within the following 15 days were lung cancer (19.3% of reconsultations), monotherapy CT (38.6%), ECOG 1 (42.1%) and infectious pathology and complications secondary to the tumor itself (28.1% each one). Factors significantly associated with lower overall survival were hospital admission (median: 16 weeks, 95% CI 3.7-28.2), diagnosis of complications secondary to the tumor itself (median: 11 weeks, 95% CI 10.3 - 23.6) and reconsultation (median: 17 weeks, 95% CI 10.3-23.6).

Conclusions

Among oncology patients admitted to the Emergency department, complications secondary to the underlying oncological disease represent the most relevant variable in the field of oncological emergencies due to their impact on the likelihood of hospitalization, reconsultation and survival.

Clinical trial identification

Editorial acknowledgement

Legal entity responsible for the study

The authors.

Funding

Has not received any funding.

Disclosure

M. Sanchez Canovas: Financial Interests, Personal, Speaker, Consultant, Advisor: Leo Pharma, Sanofi, Lundbeck, Angelini. M.A. Ivars: Financial Interests, Personal, Speaker, Consultant, Advisor: Ipsen Pharma, Pierre Fabre. All other authors have declared no conflicts of interest.