2095P - Cancer rehabilitation program for cancer-related fatigue

Background

Cancer-related fatigue (CRF) is a significant and frequent problem among cancer patients. There is no gold standard. However, ESMO CPGL 2020 recommended multimodal interventions, CRF is underdiagnosed, undertreated and underdocumented. In this study, we evaluated cancer rehabilitation program including education, physical activity and emotional support.

Methods

Cancer rehabilitation program includes: patients and family education, physical activity (aerobic exercise), water- therapy, yoga, behavioural therapy, relaxation, art, music-therapy, proteinrich nutrition, social support. The Five-time-sit-to-stand test, Hand-Grip-Strength, 6 min walking test, Brief fatigue inventory, Hospital anxiety and Depression scale were used. Descriptive statistics and t-tests.

Results

Participants were 112 patients (48y [29-75]), 60.7% women and 39.2% men. The primary cancer was 26.7 % breast, 16.9% gasrtoesophageal 33.6% colorectal, 16.8% lung, 5.96% pancreatobiliary. Before rehabilitation: the Five-time-sit-to-stand test 10.2 sec (4.5-28.1), Hand-Grip-Strength 28.4 kg, 6 min walking test 482 meters (49,631), Brief fatigue inventory 45 (0-75), Fatique 8/10 (0,10), Cognitive 6, Emotional 4, Physical 6, QoL 4 (0-10). HADS 8 (0, 18). After rehabilitation: the Five-time-sit-to-stand test 5.7 sec (-50%), Hand-Grip-Strength 39.2 kg, 6 min walking test 585 meters (62,822), Brief fatigue inventory 25 (0-58), Fatique 3/10 (0,10), Cognitive 3, Emotional 1, Physical 4, QoL 7 (0-10). HADS 4 (0, 18).

Conclusions

Cancer rehabilitation program including different types of interventions is effective in treating cancer related-fatigue.

Clinical trial identification

Editorial acknowledgement

Legal entity responsible for the study

The authors.

Funding

Has not received any funding.

Disclosure

All authors have declared no conflicts of interest.