Abstract 1700P
Background
Functional status (FS) including Activities of Daily Living (ADL) and Instrumental Activities of Daily Living (IADL) is part of the Comprehensive Geriatric Assessment (CGA).
Methods
This study was conducted between September 2015 and January 2019 at Marseille University Hospital (AP-HM). During this period, all consecutive outpatients aged 70 years or older referred for a CGA before initiation of lung and thoracic cancer treatment were enrolled. Our objective was to assess the impact of combination of the information collected with the ADL and short IADL scales on overall survival (OS) and unplanned hospitalizations within three months in older patients treated for lung and thoracic cancers.
Results
227 patients were recruited. The median age was 78.7 years and 74.0 % were male. The majority of the patients were diagnosed with non-small cell lung cancer (82%). Concerning FS, 41.9% of patients had unimpaired ADL-IADL, 26.0% had impaired IADL alone, 4.0% had impaired ADL alone, and 28.1% had impaired ADL-IADL. ADL-IADL impairment was associated with poor nutritional status, mobility, or cognitive disorders (p<0.001). In a logistic regression model, ADL or IADL impairment (OR=2.1; 95% CI [1.0-4.2]) and impaired ADL-IADL (OR=2.6; 95% CI [1.2-5.3]) were independently associated with a higher risk of unplanned hospitalizations within 3 months. In the multivariate Cox model, a decrease in OS was independently associated with impaired ADL-IADL (aHR=2.4; 95% CI [1.5-3.9]).
Conclusions
Combining the ADL and IADL scales to evaluate FS of older patients with lung or thoracic cancer could be a new efficient tool in CGA.
Clinical trial identification
Editorial acknowledgement
Legal entity responsible for the study
The authors.
Funding
Has not received any funding.
Disclosure
All authors have declared no conflicts of interest.