Abstract 1682P
Background
Prostate cancer (PrC) patients undergoing androgen deprivation therapy (ADT) may suffer from several adverse events, such as deterioration of physical fitness. The main aim of this work was to analyze the impact of walking football on muscle strength and balance in PrC survivors.
Methods
Thirty-one patients (IIb-IVb) were randomly allocated to a walking football program (WF, n=16) or usual care (UC, n=15). Patients had to be on ADT for an expected period of more than 6 months and have of evidence of osteoporosis (T score >-2.5). The WF program consisted of 3 supervised sessions per week of 90 minutes, over 16 weeks. Handgrip and lower limb maximal isometric muscle strength and static balance were assessed before (baseline, M0), during (week 8, M1) and after (week 16, M2) the interventions, using digital dynamometers, a chair sit to stand test and a single leg balance test.
Results
Fifty patients were recruited and thirty-seven included in the intention to treat analysis. The median age was 74 YO. Patients adhered on average to 85.6±14.3% of the predicted number of sessions [AJCA1]. No [ÁF(2] differences were found in balance and muscle strength between groups at baseline. In contrast, there was a significant improvement in the chair sit to stand test performance (UC: 11.0±2.0 vs. 11.9±2.2 vs. 11.7±2.9, p=0.412 vs. WF: 13.8±2.9 vs. 16.4±3.6 vs. 17.4±4.7, p<0.001) and balance in dominant (UC: 15.7±12.4 vs. 15.9±12.4 vs. 20.7±12.7, p=0.103 vs. WF: 11.6±9.7 vs. 19.4±13.1 vs. 20.1±12.7, p=0.002)| and non-dominant limbs (UC: 19.8±16.4 vs. 17.4±13.2 vs. 18.8±14.8, p=0.604 vs. WF: 11.9±10.2 vs. 20.4±15.2 vs. 21.5±14.5, p=0.008) after 8 and 16 weeks of WF, remaining unchanged in the UC group. No interaction was found across time between groups, but handgrip strength in the dominant limb (UC: 29.1±6.4 vs. 30.8±4.3 vs. 30.9±5.4, p=0.217 vs. WF: 30.7±4.8 vs. 32.7±4.8 vs. 32.2±4.6, p=0.024) and lower body strength in non-dominant limb increased after 8 weeks of WF, remaining unchanged in the UC group. Moreover, no serious adverse events were reported in the WF group.
Conclusions
A WF program improves muscular strength and balance in PrC patients undergoing ADT.
Clinical trial identification
NCT04062162.
Editorial acknowledgement
Legal entity responsible for the study
OncoMove - Associação de Investigação de Cuidados de Suporte em Oncologia (AICSO).
Funding
Federação Portuguesa de Futebol and Camara Municipal de Gaia.
Disclosure
All authors have declared no conflicts of interest.