Abstract 139P
Background
Despite the proven benefits of extended hormonal therapy for breast cancer, its acceptance among young Egyptian women under 45 remains underexplored. This study delves into their willingness to prolong treatment, considering the socio-economic and psychological factors unique to this group.
Methods
In a cross-sectional study at the National Cancer Institute, Cairo University, 583 young patients on adjuvant hormonal therapy were surveyed about extending treatment, considering side effects, benefits, and preferences.
Results
With an average age of 40.2 years, most participants were housewives; 46.5% had a family history of cancer, with a predominant Stage II diagnosis. Treatment mainly involved tamoxifen and GNRH agonists, with significant side effects like hot flushes and bone aches reported in 80% of the patients. Despite this, 54.7% were open to extending therapy, influenced by side effects, treatment duration, and diagnosis stage. Interestingly, treatment willingness did not significantly correlate with patient demographics.
Conclusions
The study reveals a positive inclination towards extended hormonal therapy among young Egyptian breast cancer patients, moderated by side effects and perceived benefit-discomfort balance. It underscores the importance of patient-centered education and support to improve adherence and outcomes. Tailored education and support programs could significantly enhance adherence to extended hormonal treatments, potentially improving long-term survival and quality of life for young breast cancer patients in Egypt.
Legal entity responsible for the study
The authors.
Funding
Has not received any funding.
Disclosure
All authors have declared no conflicts of interest.