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Poster Display session 3

2187 - Health status of middle-aged and older cancer survivors in China: results from the China Health and Retirement Longitudinal Study (CHARLS)

Date

30 Sep 2019

Session

Poster Display session 3

Presenters

Jiarui Li

Citation

Annals of Oncology (2019) 30 (suppl_5): v671-v682. 10.1093/annonc/mdz263

Authors

J. Li1, L. Zhao1, C. Bai1, H. Pang2, Z. Sun1

Author affiliations

  • 1 Department Of Medical Oncology, Peking Union Medical College Hospital, 100730 - Beijing/CN
  • 2 Central Research Laboratory, Peking Union Medical College Hospital, 100730 - Beijing/CN
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Resources

Abstract 2187

Background

The number of Chinese cancer survivors is increasing due to the trend of an aging population and improved cancer survival. It is urgently required to estimate the health status of cancer survivors and provide scientific evidence for future health care reform. This study aimed to evaluate the general health status of cancer survivors older than 45 years in China.

Methods

We identified cancer survivors (n = 354) and participants without cancer (n = 16,664) in the China Health and Retirement Longitudinal Study (CHARLS). Physical and mental health information collected by questionnaire were compared between cancer survivors and cancer-free controls.

Results

The mean age of cancer survivors was 61.0 years. More cancer survivors were female (68.9% vs. 52.3%, P < 0.001) and lived in a rural region (43.8% vs. 38.4%, P = 0.039) than those without cancer. Cancer survivors and participants without cancer did not show significant differences in age, marital status, education or BMI. The health status of middle-aged and older cancer survivors are shown in the table. Cancer survivors had more concomitant chronic diseases than participants without cancer (2.75 vs. 2.00, P < 0.001). The current health condition reported by cancer survivors themselves was poorer than no cancer group (3.87 vs. 3.38, P < 0.001). The daily activity score was higher in the cancer group (3.53 vs. 2.39, P < 0.001), which indicated that cancer survivors had more difficulties in their daily life than other middle-aged and older participants. There was no statistically significant difference in cognitive function between these two groups even after adjustment (12.61 vs. 12.90, P = 0.612). Cancer survivors had more depressive symptoms than participants without cancer after adjustment (10.07 vs. 8.01, P = 0.003).Table: 1649P

Health status of middle-aged and older cancer survivors and participants without cancer from the CHARLS

CharacteristicTotal (N = 17,018)Cancer survivors (n = 354)No cancer (n = 16,664)P valueP value
Number of concomitant chronic diseases, mean ± SD2.02 ± 1.702.75 ± 2.132.00 ± 1.69<0.001
Self-reported health score (1-5), mean ± SD3.39 ± 0.383.87 ± 0.823.38 ± 0.87<0.001<0.001
Daily activity, mean ± SD2.41 ± 3.363.53 ± 3.852.39 ± 3.35<0.001<0.001
Cognitive function, mean ± SD12.89 ± 5.6912.61 ± 5.6012.90 ± 5.690.6290.612
Depression, mean ± SD8.05 ± 6.4110.07 ± 7.068.01 ± 6.39<0.0010.003

Adjusted for age, sex, region, and number of concomitant chronic diseases.

Conclusions

The health status of middle-aged and older cancer survivors is poor in China. High-quality and cost-effective supportive care for these individuals is needed.

Clinical trial identification

Editorial acknowledgement

Legal entity responsible for the study

The authors.

Funding

National Natural Science Foundation of China (No. 61435001) and CAMS Innovation Fund for Medical Sciences (No. 2016-I2M-1-001, No. 2017-I2M-4-003).

Disclosure

All authors have declared no conflicts of interest.

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