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E-Poster Display

1222P - Spontaneous ventilation video-assisted thoracoscopic surgery for geriatric patients with non-small cell lung cancer: A propensity score matching analysis

Date

17 Sep 2020

Session

E-Poster Display

Topics

Tumour Site

Non-Small Cell Lung Cancer

Presenters

Chuqiao Wang

Citation

Annals of Oncology (2020) 31 (suppl_4): S735-S743. 10.1016/annonc/annonc282

Authors

C. Wang, D. Wu, H. Liang, Z. Lin, H. Kong, J. Zhao, X. Chen, Z. Zhao, J. He

Author affiliations

  • Department Of Thoracic Surgery And Oncology, the First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, Guangzhou, China, 510120 - Guangzhou/CN

Resources

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Abstract 1222P

Background

The feasibility and safety of spontaneous ventilation video-assisted thoracoscopic surgery (SV-VATS) in geriatric patients aged ≥60 years with non-small-cell lung cancer (NSCLC) remain unclear.

Methods

A total of 164 geriatric patients with NSCLC undergoing SV-VATS and 1238 patients undergoing mechanical ventilation video-assisted thoracoscopic surgery (MV-VATS) between April 2012 and July 2018 were analysed. We used propensity score matching (PSM) to minimize the difference in baseline characteristics. The perioperative outcomes between the SV-VATS group and MV-VATS group were compared.

Results

After PSM, 152 of 164 patients in the SV-VATS group, and 152 of 1238 patients in the MV-VATS group were matched based on similar propensity scores. There were no significant differences in anesthesia time (225 ± 94 vs 235 ± 62 min; P =0.30), surgery time (191 ± 105 vs 177 ± 80 min; P =0.24) and intraoperative bleeding (75 ± 217 vs 62 ± 120 ml; P =0.72) between two groups. After surgery, hospitalization (17 ± 7 vs 16 ± 7 days; P =0.30), chest tube duration (6 ± 9 vs 4 ± 2 days; P =0.366) and incidence of complications (7% vs 10%; P =0.41) were non-significant and comparable between both groups.

Conclusions

In this study, SV-VATS proved to be feasible and safe in the geriatric patients with NSCLC. Further investigation is required to evaluate the long-term effects of SV-VATS in geriatric patients with NSCLC.

Clinical trial identification

Editorial acknowledgement

Legal entity responsible for the study

The First Affiliate Hospital of Guangzhou Medical University.

Funding

Has not received any funding.

Disclosure

All authors have declared no conflicts of interest.

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