Abstract 22P
Background
Colorectal cancer (CRC) is the third most diagnosed cancer in males and second in females all around the world. Surveillance programs are necessary to early detection recurrences, as 30% to 50% of patients treated for localized colorectal cancer will relapse. The aim of our study is to evaluate if prolonging the follow up more than five years is justified.
Methods
We retrospectively analyzed data from 573 patients diagnosed with localized CRC between 2009 and 2014. The follow up lasted until January 2024. We have analyzed the incidence of relapse and second tumors.
Results
Most of patients were men (55.92%), at a median age of 77. The stage IIA was the most frequent (41.64%) followed by IIIB (30.14%). The 52.79% of patients had a right side CCR. Chemotherapy was administrated to 261 patients (45.47%). Tumor recurrence was observed in 126 patients (21.95%). Liver relapse was the most frequent (27.27%) followed by pulmonary relapse (23.64%). Only 24 patients (4.18%) had local recurrence. Data show more relapses in patients with stage IIA (p 0.008) and IIIB (p 0.009). Recurrences after five years were observed in only 8 patients (6.35%) 2 being local, 2 hepatic and 4 pulmonary. Second tumors were diagnosed in 82 patients (11.89%). After five years of follow up we detected 10 patients with a second tumor and 2 with a relapse CCR and another tumor.
Conclusions
This study shows that tumor recurrences appear in 21.95% of patients, 6% of which after the 5 years follow up recommended in the guidelines, mostly on patients with stage IIA, suggesting the need to further study risk factors of this population and assess the need of further follow up.
Legal entity responsible for the study
The authors.
Funding
Has not received any funding.
Disclosure
All authors have declared no conflicts of interest.