CN33 - G-8 geriatric screening tool and geriatric nutritional risk index

Background

Comprehensive geriatric assessment of older cancer patients is important for predicting prognosis and survival. However, the long duration of the assessment makes it difficult to apply in the clinic. However, it has been reported that the G8 screening tool and the Geriatric Nutritional Risk Index (GNRI), which could be applied in a shorter time, can be used in the elderly. The aim of this study was to compare the overall survival (OS) of older people diagnosed with cancer using the G8 screening tool and GNRI scores.

Methods

A total of 250 (33.6% female and 66.4% male) geriatric oncology patients were assessed with the G8 screening tool and the GNRI at the time of diagnosis. The mean age of the patients was 72.1±5.0 (65-87) years. The most prevalent types of cancer were lung (23.6%), colorectal (21.2%) and breast (10.4%). According to the score obtained from G8 screening tool, patients were divided into two groups: “normal” (>14) and “anormal” (≤14). The GNRI was calculated using serum albumin, current and ideal body weight. According to the GNRI score, patients were divided into four groups: high risk (<82), intermediate risk (82-92), low risk (92-98) and no risk (>98).

Results

The median OS of patients with normal and anormal G8 score was 30.9 (95% CI 18.1-43.1) and 11.7 (95% CI 9.2-14.1) months, respectively (p<0.001). According to the GNRI score, the median OS for high risk, intermediate risk, low risk and no risk patients were 0.9 (95% CI 0.7-1.2), 6.6 (95% CI 3.7-9.6), 11.4 (95% CI 6.1-16.8) and 26.9 (18.4-35.4) months, respectively (p<0.001).

Conclusions

The OS was found to be shorter in older cancer patients with low G8 and GNRI scores. The use of the G8 screening tool and the GNRI at the time of diagnosis in elderly patients with cancer could be used to make an objective prediction of life expectancy.

Clinical trial identification

Editorial acknowledgement

Legal entity responsible for the study

The authors.

Funding

Has not received any funding.

Disclosure

All authors have declared no conflicts of interest.