Abstract 5010
Background
Although immunotherapy treatment (ImT) supposes a great advance for cancer patients, it also presents a challenge to health professionals, not only because of their adverse-event profile differs from chemotherapy or radiotherapy but, because it introduces new areas of clinical practice. All Immunotherapy Clinical Guidelines highlight the importance of prevent adverse effects related-IrAE, education and monitoring patients is crucial. In 2018 the Catalan Institute of Oncology (ICO), along with 4 European oncology institutions launched the VIKHI project, (Virtual International Knowledge Hub in Inmuno-Therapy) to improve care delivery, education of professionals and patients on receiving ImT through a comprehensive training program. Objective: cross-sectional study evaluating knowledge that patients have about their immunotherapy treatment.
Methods
From July 2018-March 2019, all patients treated with ImT first time were recruited non-probabilistic sample. They had to answer 10 questions about their knowledge on disease & treatment, and quality of life with EORTC-QLC30 scale. The interviews were conducted by clinical nurse specialist.
Results
A total of 85 patients. By tumors; lung 74.11%, head-neck 7.05%, melanoma 5.88%, renal 3.52% and double tumors 9.41%. They received ImT as part as their standard treatment in 62.35% and 37.64% as clinical trial and in 31.77% were their first treatment. 91.76% patients were knowledgeable about receiving ImT, but only 3.52% were not aware and 4.70% describe Chemo+ImT. About being able to identify complications, diarrhoea was the most described by 25.23%, followed by skin problems by 23.38%, thyroid problems and fever 13.53% and alopecia by 0.30%. Only two patients were unable to identify any. Informed by oncologist 63.5% and by nurses 32.9%. Only 7% of patients considered being fully informed.
Conclusions
Still room to improve about patient education and communication for patients receiving ImT. It would be important to train the HCP’s, especially nurses, so that they can effectively inform and educate patients.
Clinical trial identification
Editorial acknowledgement
Legal entity responsible for the study
Catalan Institute of Oncology.
Funding
Independent Educational Grant from Pfizer IGCL Grant ID: 34096003.
Disclosure
All authors have declared no conflicts of interest.
Resources from the same session
1908 - Androgen Receptor (AR) Aberrations in Patients (Pts) With Metastatic Castration-Sensitive Prostate Cancer (mCSPC) Treated With Apalutamide (APA) Plus Androgen Deprivation Therapy (ADT) in TITAN
Presenter: Kim Chi
Session: Poster Display session 3
Resources:
Abstract
4058 - 68Ga-PSMA guided bone biopsies for molecular diagnostics in metastatic castration resistant prostate cancer patients
Presenter: Anouk de Jong
Session: Poster Display session 3
Resources:
Abstract
2226 - Spatial-Temporal Change in Quantitative Total Bone Imaging (QTBI) and Circulating Tumor Cells (CTCs) in Metastatic Castration-Resistant Prostate Cancer (mCRPC) Treated With Enzalutamide (ENZA)
Presenter: Glenn Liu
Session: Poster Display session 3
Resources:
Abstract
5795 - Efficacy of Enzalutamide in Hormone-sensitive Metastatic Prostate Cancer: Clinical Utility of 18F-Choline PET and Whole Body MRI.
Presenter: Susanne Osanto
Session: Poster Display session 3
Resources:
Abstract
899 - Urine extracellular vesicle GATA2 mRNA alone and in a multigene test predicts initial prostate biopsy result
Presenter: Jungreem Woo
Session: Poster Display session 3
Resources:
Abstract
3094 - Circulating tumor cell (CTC) genomic landscape in neuroendocrine prostate cancer (NEPC) by single cell copy number analysis
Presenter: Vincenza Conteduca
Session: Poster Display session 3
Resources:
Abstract
2527 - Circulating Tumor Cells (CTC) count and Prostate-Specific Antigen (PSA) response measures in metastatic Castration-Resistant Prostate Cancer (mCRPC) patients (pts) treated with Docetaxel (Doc)
Presenter: Rebeca Lozano Mejorada
Session: Poster Display session 3
Resources:
Abstract
6106 - Assessing the clinical relevance of drug–drug interactions (DDI) with darolutamide (DARO)
Presenter: Christian Zurth
Session: Poster Display session 3
Resources:
Abstract
2237 - KEYNOTE-921: phase 3 study of pembrolizumab (pembro) plus docetaxel and prednisone for enzalutamide (enza)- or abiraterone (abi)-pretreated patients (pts) with metastatic castration-resistant prostate cancer (mCRPC).
Presenter: Daniel Petrylak
Session: Poster Display session 3
Resources:
Abstract
2241 - KEYNOTE-641: Phase 3 Study of Pembrolizumab (pembro) Plus Enzalutamide for Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Presenter: Julie Graff
Session: Poster Display session 3
Resources:
Abstract