Abstract 613P
Background
Physicians have frequent interactions with the pharmaceutical industry (pharma), however, there is concern for possible corporate influence on physicians’ prescribing behaviours. We sought to understand perceptions and interactions between pharma and medical oncologists (MO), in comparison with infectious diseases (ID) physicians.
Methods
We conducted an anonymous online cross-sectional survey of Australian MO and ID physicians comparing self-reported interactions and attitudes with pharma. An additional survey was undertaken at Tan Tock Seng Hospital, Singapore.
Results
A total of 204 Australian and Singaporean physicians were surveyed including 102 oncologists and 102 ID physicians. Demographics including age, gender and years of practice between the two Australian specialties were similar, with an exception that most ID physicians had mainly public work (95% vs. 78% for oncologists, p<0.001). Oncologists had more frequent contact with pharma, the majority (69%) negotiating compassionate access for patients on a monthly/annual basis, compared with ID physicians who had never done so (45%), p<0.001. More ID physicians had never attended a sponsored meeting (15% ID vs. 27% MO respectively, p=0.01) or received travel/accommodation grants from pharma (42% ID vs. 85% MO respectively, p<0.001). However, most physicians (92%) had never received gifts from pharma, with no difference between groups (p=0.17). Most Australian oncologists believed that interacting with pharma was overall beneficial for patient care (78%) compared to ID physicians (34%, p<0.001). This statement was shared by 71% of Singaporean oncologists. Similar rates of Australian oncologists and ID physicians (83% vs. 88%, respectively) felt comfortable for patients to know the details of their interactions with pharma, however, only 57% of Singaporean oncologists agreed with this statement. Most Australian respondents (77%) agreed that there was strong public skepticism of these interactions (p=0.35).
Conclusions
Medical oncologists had more interactions with pharma than ID physicians and were more likely to believe that this was overall beneficial to patient care despite the negative public perception associated with this.
Clinical trial identification
Editorial acknowledgement
Legal entity responsible for the study
The authors.
Funding
Has not received any funding.
Disclosure
P.L. Chia: Financial Interests, Personal, Advisory Board: Merck, Roche, Pfizer, Amgen; Financial Interests, Institutional, Research Funding: Merck, Roche, Pfizer, Amgen. T. John: Financial Interests, Personal, Invited Speaker, Speaker tour Vietnam: AstraZeneca; Financial Interests, Personal, Invited Speaker, CTIO: Merck Sharp Dohme; Financial Interests, Personal, Advisory Board: BMS, AstraZeneca, Bayer, Specialised Therapeutics; Financial Interests, Institutional, Advisory Board: Roche, Novartis, Pfizer, Amgen, Takeda, PharmaMar; Financial Interests, Personal, Other, Speaker/Chair: ACE Oncology. All other authors have declared no conflicts of interest.
Resources from the same session
560P - Triple-targeted therapy of dabrafenib, trametinib and osimertinib for the treatment of acquired BRAF V600E mutation after progression on EGFR-TKIs in advanced EGFR-mutant NSCLC
Presenter: Chengdi Weng
Session: Poster Display
Resources:
Abstract
561P - Mechanisms of osimertinib resistance using circulating tumor DNA analyses for EGFR-mutated non-small cell lung cancer, results from ELUCIDATOR: A prospective observational multicenter study
Presenter: Daijiro Harada
Session: Poster Display
Resources:
Abstract
562P - First-line (1L) osimertinib (osi) ± platinum-pemetrexed in patients (pts) with EGFRm advanced NSCLC: FLAURA2 China cohort
Presenter: Yan Yu
Session: Poster Display
Resources:
Abstract
563P - Real-world effectiveness and safety of first-line osimertinib for EGFR-mutated advanced NSCLC in China (FLOURISH study)
Presenter: Jianya Zhou
Session: Poster Display
Resources:
Abstract
564P - Co-occurring EGFR p.E709X mutation affects the treatment response to the third-generation EGFR-TKIs in EGFR p.G719X-mutant patients with advanced NSCLC
Presenter: Wen Feng Fang
Session: Poster Display
Resources:
Abstract
565P - Genome-guided targeted therapy combination improves survival in patients with advanced EGFR mutation positive NSCLC failing osimertinib
Presenter: Molly Li
Session: Poster Display
Resources:
Abstract
566P - Safety of tepotinib + osimertinib in EGFR-mutant NSCLC with MET amplification after first-line osimertinib
Presenter: Chong Kin Liam
Session: Poster Display
Resources:
Abstract
567P - Furmonertinib in combination with bevacizumab and intrathecal chemotherapy as later-line re-challenge treatment in EGFR –mutated NSCLC patients with leptomeningeal metastasis after third-generation EGFR-TKIs treatment failure
Presenter: Fang Cun
Session: Poster Display
Resources:
Abstract
568P - First-line (1L) osimertinib + platinum-pemetrexed in EGFR-mutated (EGFRm) advanced NSCLC: Updated FLAURA2 safety run-in (SRI) results
Presenter: David Planchard
Session: Poster Display
Resources:
Abstract
569P - Whole-transcriptome sequencing of transformed small-cell lung cancer from EGFR-mutated lung adenocarcinoma reveals LUAD–like and SCLC–like subsets
Presenter: Chan-Yuan Zhang
Session: Poster Display
Resources:
Abstract