Abstract 159P
Background
Obesity is a risk factor for several cancer. In Korea, prevalence of obesity has increased and incidence of several cancers of gastrointestinal (GI) tract, such as colon cancer and rectal cancer have increased. The aim of this study was to evaluate the association between obesity prevalence and cancer incidence of gastrointestinal tract in Korea adults.
Methods
The data were collected from the webpage of Statistic Korea, where the incidence of GI tract cancer between 2001 and 2016 was obtained from National Cancer Center, and the prevalence of obesity between 2001 and 2016 was obtained from National Health and Nutrition Examination Survey. The obesity was defined as BMI ≥25 kg/m2 among adults ≥30 years old. The association between obesity and cancer of GI tract was calculated by using linear regression analysis.
Results
In men, prevalence of obesity was significantly associated with esophageal cancer (β: 0.176, P = 0.001), colon cancer (β: 2.034, P = 0.013), rectal cancer (β: 1.305, P = 0.035), gallbladder cancer and other biliary tract cancer (β: 0.712, P < 0.0001), and pancreatic cancer (β: 0.717, P < 0.0001). But, gastric cancer (β: 1.396, P = 0.076) and liver cancer (β: 0.122, P = 0.496) were not associated with obesity prevalence (Table) In women, incidence of GI tract cancer was not associated with obesity prevalence.Table:
159P Linear regression between obesity and GI cancer in men adults
Cancer | Beta coefficient | 95% CI | P value |
---|---|---|---|
Esophageal cancer | 0.167 | 0.092 - 0.241 | 0.001 |
Gastric cancer | 1.396 | -1.76 - 2.968 | 0.076 |
Colon cancer | 2.034 | 0.535 - 3.533 | 0.013 |
Rectal cancer | 1.305 | 0.114 - 2.495 | 0.035 |
Liver cancer | 0.122 | -0.262 - 0.506 | 0.496 |
Gallbladder and other biliary tract cancer | 0.712 | 0.498 - 0.927 | <0.0001 |
Pancreatic cancer | 0.717 | 0.434 - 0.999 | <0.0001 |
Conclusions
In Korean adults, incidence of some GI tract cancer seems to be associated with obesity prevalence.
Clinical trial identification
Editorial acknowledgement
Legal entity responsible for the study
The authors.
Funding
Has not received any funding.
Disclosure
All authors have declared no conflicts of interest.
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