Abstract YO29
Case summary
A 72-year-old Japanese man presented with symptoms of chest pain and poor appetite. Contrast-enhanced CT scan showed a solid mass (diameter:80mm) with slight enhancement located in the left inferior posterior mediastinum. The mass surrounded the descending aorta at the T8-T10 level, partly infiltrating the aorta. Primary mediastinal undifferentiated sarcoma was diagnosed by CT-guided percutaneous needle biopsy. No distant metastasis was apparent on whole diffusion MRI. He was scheduled to undergo chemo radiotherapy, but 3weeks after the diagnosis, sudden anuria was observed, and his blood test revealed acute kidney injury and hyperkalemia. Contrast-enhanced CT-scan revealed occlusion of bilateral renal artery at its origin, and hemodialysis was immediately performed. We suspected that occlusion was caused by tumor embolism. The patient received catheter-directed thrombolysis to improve his renal function and to confirm diagnosis. Tumor cells identifiable as primary lesion were pathologically recognized from a part of the embolus collected by the catheter, which proves acute kidney injury secondary to bilateral renal artery tumor thrombosis. After the treatment, the renal dysfunction remarkably improved and he was able to be taken off dialysis.
Intravascular tumor thrombus often occurs in the venous system. However, we present a rare case of undifferentiated sarcoma patient with mediastinal origin that developed acute kidney injury due to bilateral renal artery tumor thrombosis and successfully treated with catheter-directed thrombolysis.
Clinical trial identification
Editorial acknowledgement
Resources from the same session
248P - Retrospective review of metastatic carcinoma of cervix from a tertiary cancer institute of south India
Presenter: Arkoprovo Halder
Session: Poster display session
Resources:
Abstract
249P - Accuracy of endometrial biopsy by Pipelle: A systematic review and meta-analysis
Presenter: Jinhai Gou
Session: Poster display session
Resources:
Abstract
250P - Non-endometrioid endometrial cancer: Analysis of different adjuvant treatment modalities
Presenter: Gonçalo Nogueira da Costa
Session: Poster display session
Resources:
Abstract
251P - A prognostic index model for predicting long-term recurrence of uterine leiomyoma after initial myomectomy in women aged 18-44 years
Presenter: Xiu Ming
Session: Poster display session
Resources:
Abstract
252P - Uterine sarcomas in Qatar: Clinico-pathological characteristics and treatment outcome
Presenter: Ashraf Fadlelseid
Session: Poster display session
Resources:
Abstract
253P - Anti-PD-1-induced reinvigoration of tumour-infiltrating CD8+ T cells in epithelial ovarian cancer patients is correlated with T cell factor-1
Presenter: Junsik Park
Session: Poster display session
Resources:
Abstract
254P - Cyclin E1 is a shared biomarker of subsets of high grade serous ovarian cancer (HGSOC) and basal like breast cancer (BLBC)
Presenter: Diar Aziz
Session: Poster display session
Resources:
Abstract
255P - MEX3A is a prognostic biomarker and correlates with RNA splicing and cell proliferation in endometrial cancer by analysis of RNA-seq data
Presenter: Huining Jing
Session: Poster display session
Resources:
Abstract
256P - Lnc-AL445665.1-4 may be involved in the development of multiple uterine leiomyoma through interacting with miR-146b-5p
Presenter: E Yang
Session: Poster display session
Resources:
Abstract
257P - Treatment results of low risk gestational trophoblastic neoplasia (GTN) from a tertiary hospital, Chennai, India
Presenter: Rakesh M. P
Session: Poster display session
Resources:
Abstract