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Xerophthalmia , conjunctivitis and Blepharitis can be managed with artificial tears, trimming of the eyelashes, topical antibiotics and topical corticosteroids (eye drops or ointment). When superinfection with S. aureus occurs, a swab is taken and an oral anti-staphylococcal antibiotic may be added. Refractory cases should be referred to an ophthalmologist as complications such as corneal ulcers may occur.1
Tetracycline or antiseptic mouthwash alleviates stomatitis symptoms. For aphthous ulcers of the mouth, topical steroids or anaesthetics may be used.2
Dryness of the nose responds fairly well to lubricants or ointments containing an antibiotic or antiseptic.2
Dry genital skin areas (eg vulvovaginitis, balanitis) may be treated with moisturising creams and specific supportive agents (eg mild oestrogen-containing creams for the vulva and vagina).2


  • Artificial tears.
  • Dexamethasone eye drops.
  • Fusidic acid eye gel.
  • Chlorhexidine mouthwash.
  • Tetracycline mouthwash.
  • Betamethasone valerate 0.1% in orabase for aphthous mouth ulcers.
  • Chlorhexidine ointment for nasal dryness.
  • Oestrogen vaginal cream, Döderlein supplement.


1Melichar B & Nemcová I. Eur J Cancer Care (Engl) 2007; 16: 439-443.
2Segaert S et al. Eur J Cancer 2009; 45(Suppl 1): 295-308.

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