As nanostring is a panel-based approach, there is no need to run multiple individual FISH or RT-PCR tests for single genes or single fusion variants . In addition, nanostring has high specificity and provides rapid results yet allows complete characterisation of the NTRK gene fusions. Nanostring also provides easier data analysis compared with NGS.
- Chang KTE, Goytain A, Tucker T et al. Development and Evaluation of a Pan-Sarcoma Fusion Gene Detection Assay Using the NanoString nCounter Platform. J Mol Diagn 2018; 20: 63-77.