The advantages of DNA-based NGS are those common to all NGS techniques as well as those specific to the DNA-based NGS. The advantages of DNA-based NGS are summarised in the following table.
Table 21: Advantages of DNA-based NGS for Testing for NTRK Gene Fusions
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- Zehir A, Benayed R, Shah RH et al. Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients. Nat Med 2017; 23: 703-713.
- Beadling C, Wald AI, Warrick A et al. A Multiplexed Amplicon Approach for Detecting Gene Fusions by Next-Generation Sequencing. J Mol Diagn 2016; 18: 165-175.