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Poster display

157 - The role of citrus peel extract in inhibiting progression and recurrence of prostate cancer

Date

05 Mar 2018

Session

Poster display

Presenters

Balakrishnan Shammugasamy

Citation

Annals of Oncology (2018) 29 (suppl_3): iii10-iii34. 10.1093/annonc/mdy047

Authors

B. Shammugasamy1, P. Valtchev1, F. Dehghani1, Q. Dong2

Author affiliations

  • 1 School Of Chemical And Biomolecular Engineering, The University of Sydney, 2000 - Sydney/AU
  • 2 Sydney Medical School And Charles Perking Centre, The University of Sydney, 2006 - Sydney/AU
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Resources

Abstract 157

Prostate cancer (PC) is one of the leading cause of cancer related deaths in men. PC progression and recurrence following initial treatments possesses mortality threat amongst these patients. Cell cycle re-entry of quiescent cancer cells has been suggested for cancer progression and recurrence. The slow progression of PC allows a window of opportunity for intervention through diet. An inverse association of flavonoids intake and PC development has been demonstrated in epidemiological studies. We hypothesized that citrus peel that is rich in various bioactive compounds including flavonoids may impede cell cycle re-entry by quiescent PC cells.

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