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Poster display

77 - The role of Topoisomerase II-α (TOPO IIA) as a predictive factor for response to neoadjuvant anthracyclines based chemotherapy in locally advanced breast cancer


05 Mar 2018


Poster display


Mohamed Gamea


Annals of Oncology (2018) 29 (suppl_3): iii10-iii34. 10.1093/annonc/mdy047


M.M. Gamea

Author affiliations

  • Clinical Oncology, gharbia cancer society, 31116 - tanta/EG


Abstract 77

Topoisomerase II-α is a molecular target of anthracyclines; several studies have suggested that topoisomerase II-α expression is related to response to anthracycline treatment. The objective of this study was to evaluate whether topoisomerase II-α overexpression predicts response to anthracycline treatment in locally advanced breast cancer patients.

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