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Poster display

242 - Targeted Anticancer Therapy and Concomitant Hypofractionated Radiotherapy in Breast Cancer


05 Mar 2018


Poster display


Elisabetta Bonzano


Annals of Oncology (2018) 29 (suppl_3): iii10-iii34. 10.1093/annonc/mdy047


E. Bonzano, M. Guenzi, R. Corvò

Author affiliations

  • Radiation Oncology, IRCCS Policlinico San Martino and University, 16132 - Genova/IT


Abstract 242

HER-2 positive breast cancer represents 20% of breast cancers. If untreated, they have a worse prognosis than HER-2-negative tumors, but adjuvant therapy with trastuzumab (TSZ) improves survival. This treatment is usually well tolerated. The more frequent adverse event (30%) is asymptomatic decrease in left ventricular ejection fraction (LVEF), evaluated in our experience by echocardiogram at the start and the end of TSZ.

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