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ESMO Virtual Advanced Course on NTRK Gene Fusion: A New Target in Precision Treatment of Cancer 2020

23 - 24 Nov 2020


Advanced Course on NTRK Gene Fusion 1000x1000

Slides and webcasts from all ESMO Preceptorship courses are open to all with at least a free ESMO account, according to the presenters' agreement to release them. ESMO thanks the authors for their generosity.

The use of these presentations is for personal educational purposes only.

Learning Objectives
  • Acquire knowledge of the TRK family members and their roles in ontogenesis
  • Understand the mechanisms of gene fusion and the different fusion partners involved
  • Learn how TRK receptors are structured and how their activation impacts signal transduction
  • Review the epidemiology of NTRK gene fusion in human tumours
  • Understand the methodology to identify NTRK gene fusion and the challenges of testing
  • Update knowledge on the present outcome obtained with NTRK inhibitors, their toxicities and clinical management

This event has been supported by an unrestricted educational grant from Bayer.

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There are 12 resources available

Welcome and introduction

Presenter: C. Marchio, IT, D. S. P. Tan, SG

Session: Welcome and Introduction




Present results with larotrectinib

Presenter: U. N. Lassen, DK

Session: SESSION 4 – Clinical development of NTRK inhibitors – Part 1




Workshop 2 for pathologists

Presenter: C. Marchio, IT, K. T. E. Chang, SG

Session: Workshop sessions




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