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Poster Display & Cocktail

26P - Genome-wide virus-integration map reveals a common oncogenic insertional mechanism of HPV, HBV, and EBV

Date

02 Mar 2020

Session

Poster Display & Cocktail

Presenters

Rui Tian

Citation

Annals of Oncology (2020) 31 (suppl_1): S10-S13. 10.1016/annonc/annonc85

Authors

R. Tian, Z. Cui, Z. Jin, Z. Hu

Author affiliations

  • 1st Affiliated Hospital of Sun Yat-sen University, 510000 - Guangzhou/CN
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Resources

Abstract 26P

Oncogenic virus infections contribute to approximately 15% of the total cancer burden, causing 1.6 million new malignancies annually. HPV, HBV, and EBV are the three most hazardous oncogenic DNA viruses. One common feature is the insertion of their DNA into the human genome to further promote tumorigenesis. However, the insertional patterns and mechanisms are still poorly understood.

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