Abstract 193P
Background
Metastatic carcinoma of Gallbladder is a notoriously lethal malignancy and its treatment remains an enigma for the patient as well as for the treating oncologist. In India, it is most prevalent in the northern and north eastern states of Uttar Pradesh, Bihar, Orissa, West Bengal and Assam. We have reported here clinicoepidemiological profile of 142 patients having metastatic carcinoma of gall bladder.
Methods
The study comprised 142 GBC cases referred to the tertiary care centre in Kolkata, India during 2017-19. Detailed history and clinical examination followed by requisite investigations were done for the patients and were treated as per the existent guidelines.
Results
Out of 142 patients 116 (81.6%) were females while 26 (18.4%) were males. The mean age for females was 58 while for male 46 years. Total 18 (12.6%) patients had presented in poor general condition and were managed with best supportive care. The commonest presentations were abdominal pain (81%), weight loss (72%), obstructive jaundice (30%), ascites (27%) and anorexia (21%). The commonest site of metastasis were liver (87%), Ascites (30%), retroperitoneal lymphadenopathy (28%) and left supraclavicular lymphadenopathy (17%). Rare sites of metastasis were lung, brain and skeletal deposits.
Conclusions
Our study provided a clinicoepidemiological profile of patients having metastatic carcinoma gall bladder in North east India for the first time. Most of our patients presented or had history of gall bladder stone. We have tried to study various risk factors associated with the disease. Unfortunately a significant number of patients presents very late in our setting and due to non availability of effective chemotherapy or targeted therapy mortality remains very high. As the incidence of this malignancy is increasing it is the need of the hour to study various therapies for effective management of this malignancy.
Clinical trial identification
Editorial acknowledgement
Legal entity responsible for the study
The author.
Funding
Has not received any funding.
Disclosure
The author has declared no conflicts of interest.
Resources from the same session
74TiP - Phase I study of BI 836880, a VEGF/Ang2-blocking nanobody®, as monotherapy and in combination with BI 754091, an anti-PD-1 antibody, in Japanese patients (pts) with advanced solid tumours
Presenter: Kentaro Yamazaki
Session: Poster display session
Resources:
Abstract
75P - A parallel deep learning network framework for whole-body bone scan image analysis
Presenter: Xiaorong Pu
Session: Poster display session
Resources:
Abstract
76P - Perception and satisfaction of cancer patients in clinical trials
Presenter: Jukyung Jeon
Session: Poster display session
Resources:
Abstract
77P - A prognostic nomogram for the prediction of neuroblastoma
Presenter: Jian-Guo Zhou
Session: Poster display session
Resources:
Abstract
80P - The clinical usefulness of a new fat-dissociation method to detect lymph nodes from surgically resected specimen in colorectal cancer: Prospective randomized study
Presenter: Shiki Fujino
Session: Poster display session
Resources:
Abstract
81P - Concurrent or consolidation chemotherapy during radiation as neoadjuvant treatment for locally advanced rectal cancer: A propensity score analysis from two prospective study
Presenter: JianWei Zhang
Session: Poster display session
Resources:
Abstract
82P - Body mass index, tumour location, and colorectal cancer survival
Presenter: Dake Chu
Session: Poster display session
Resources:
Abstract
83P - Helicobacter bilis may play a role in the carcinogenesis of colitis associated colon cancer correlating to increased number of CD4+CD45RB+ T cells
Presenter: Xiangsheng Fu
Session: Poster display session
Resources:
Abstract
84P - Comprehensive evaluation of relapse risk (CERR) score for colorectal liver metastases development and validation
Presenter: Jianmin Xu
Session: Poster display session
Resources:
Abstract
85P - Which is the best partner for capecitabine-based neoadjuvant chemoradiotherapy in locally advanced rectal cancer? A retrospective analysis of a comprehensive cancer center
Presenter: Jingwen Wang
Session: Poster display session
Resources:
Abstract