A pilot trial in 10 cervical carcinoma patients undergoing chemoradiation was conducted.
The intervention consisted of a one hour duration yoga program, conducted 6 days a week for 6 weeks. Feasibility was measured by adherence. Acceptability was assessed by questionnaires. Efficacy measures included changes in blood pressure, weight, haemoglobin, platelet, and lymphocyte count which were recorded once weekly.
Recruitment was accomplished as planned. All patients consented to the study. The majority of study subjects (90%) completed the trial. Of those who completed the trial, 8 attended 30 days or more of the 36 yoga sessions conducted. Subjects were satisfied with the study and the practices and 75% continued to practice yoga at home for 1 month after the study. From baseline to 6th week, the results show evident reduction in stress, anxiety, depression and an improved quality of life. The fatigue scores were recorded to be slightly higher on the days patients received chemotherapy. No other adverse events were observed during the course of the study.
This pilot trial demonstrates the feasibility of yoga in cervical cancer patients without prior yoga experience. The subject retention and satisfaction show high rates of acceptability suggesting that yoga is an acceptable intervention in this population. The results show that larger randomized controlled studies would be safe and feasible to be conducted with a bigger sample to provide a strong ground to show better efficacy of the practice.
Legal entity responsible for the study
Hospital Ethical committee
Ministry of Ayush, Govt of India.
M. Roy, H.B. Govardhan, N.K. Nelson, I. Khaleel, P. Sridhar: Acknowledgement- this project is completely sponsered by Ministry of AYUSH, Govt of INDIA.