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Poster lunch

2096 - Survival pattern of primary heart cancer (539P)

Date

18 Nov 2017

Session

Poster lunch

Presenters

eman Ramadan

Citation

Annals of Oncology (2017) 28 (suppl_10): x166-x168. 10.1093/annonc/mdx677

Authors

E. Ramadan1, A. Meshref2

Author affiliations

  • 1 Cardiology, Zagazig General Hospital, 273301 - Zagazig/EG
  • 2 General Practitioner, Suez Canal University Hospital, 41522 - Ismailia/EG
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Resources

Abstract 2096

Background

Primary malignancy of the heart are one of the rare tumors. This study aimed to show factors that affecting the survival rate of those patient with primary heart malignancy.

Methods

All 18 SEER registries database was used to obtain data of patient who diagnosed with primary malignant heart tumors between 2000 – 2013. One-year relative survival rates was by Kaplan-Meir method. We compared relative survival rates among groups of patients according to different variables.

Results

389 patients met the selection criteria in SEER database. The result showed that primary malignant heart tumors is most common in white race (75.6%), male gender (54.8%) and (40-79y) age group (62%). (>40 y) age group showed significant (P value =0.003) high one-year relative survival rate] 61% (51%-69.6%) [. Hemangiosarcoma (9120/3) was the most frequent histological type (29.3%). Although fibromyxosarcoma (8811/3) showed on of lowest frequent histological type, it shows high significant (P value =0.003) one-year relative survival rate] 83.8% (48.7%-95.7%) [. Overall comparison of different modalities of treatment showed insignificant difference (P value =0.094) of one-year relative survival rate. Although surgical intervention showed significant (P value > 0.001) increase in one-year relative survival rate] 67.1% (28.1%-88.2) [of moderately differentiated; Grade II cardiac cancer comparing with another treatment modalities. Also surgical intervention combined with radiotherapy showed significant (P value =0.007) increase in one year relative survival rate] 43% (14%-69.6%) [of poorly differentiated; Grade III cardiac cancer comparing with another treatment modalities].

Conclusions

Solitary surgical intervention modality of treatment is recommended in patient with grade II primary heart disease unlike combination of surgical intervention and radiotherapy with grad III of primary heart cancer which showed highest one-year survival rate.

Clinical trial identification

Legal entity responsible for the study

Eman Ramadan

Funding

None

Disclosure

All authors have declared no conflicts of interest.

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