Abstract 2041
Background
Breast cancer is a major public health problem and is the most commonly diagnosed cancer in Myanmar women who have lived around Naypyitaw Region. High rate of breast cancer in developed countries are associated with increase prevalence of known risk factors like nulliparity or low parity where as higher parity might account of relative lower incidence of breast cancer. Although menopause itself is not associated with an increased risk of developing cancer, two main factors (increasing age and obesity) are linked with a higher risk of cancer after menopause. Since Myanmar is developing country, we want to know that these risks are also observed in our patients. We aimed to evaluate the differences and similarities in the risk factors of female breast cancer according to menopausal status and parity with previous establish data.
Methods
Data from 230 breast cancer women who have registered at Naypyitaw General Hospital, Oncology ward from January 1st to the end of 2016 were reviewed and analyzed.
Results
Out of 230 patients, 91 patients (39.56%) were premenopausal (age range (25-48) years) and 139 patients (60.43%) had reached menopause (age range (40-82) years). Among nulliparous or single patients, 26 patients (36.61%) were premenopausal and 45 patients (63.38%) were postmenopausal. For the parous women, 67 patients (42.13%) were premenopausal and 92 patients (57.86%) were postmenopausal. According to the parity, single or nulliparous were found in 71 patients (30.86%), primiparous in 20 patients (8.69%), parity (2-4) in 109 patients (47.39%) and parity ≥5 in 30 patients (13.04%).Table: 570P
Parity risk with breast cancer
| Parity | Patients (%) |
|---|---|
| Nulliparous or Single | 71 (30.86%) |
| Primiparous | 20 (8.69%) |
| Multiparous | 139 (60.43%) |
Conclusions
In this study, most of our patients are postmenopausal and this finding supports the previous established data. But the majority of our breast cancer patients are multiparous and this finding is deviated from the established fact that multiparous is a protective factors against breast cancer. But we don’t yet have a conclusive issue to this, as our findings are based only on Naypyitaw region only. Further studies are required to confirm this finding.
Clinical trial identification
Legal entity responsible for the study
Naypyitaw General Hospital
Funding
None
Disclosure
All authors have declared no conflicts of interest.