Oops, you're using an old version of your browser so some of the features on this page may not be displaying properly.

MINIMAL Requirements: Google Chrome 24+Mozilla Firefox 20+Internet Explorer 11Opera 15–18Apple Safari 7SeaMonkey 2.15-2.23

Poster presentation 1

624 - Sequelae of germ cell teratoma: Experience of two challenging clinical cases


19 Dec 2015


Poster presentation 1


Mukur Ray


M.D. Ray, P.K. Garg

Author affiliations

  • Surgicall Oncology, All India Institute of Medical Sciences, 110029 - Delhi/IN


Abstract 624

Case Summary

The growing teratoma syndrome (GTS) is a rare condition seen in germ cell tumours (GCT) patients who present with progressive increasing masses during or after appropriate chemotherapy with normalized serum markers. We present two most challenging aspects of management of sequelae of germ cell teratoma - growing teratoma syndrome and transformation of teratoma into other somatic malignancies.

Case 1: An 18-years-old boy, diagnosed as a case of non-seminomatous GCT right testis Stage IIB, underwent 3cycles of BEP following orchidectomy. Post-chemotherapy CT scan revealed a 5-cm conglomerate lymph nodal mass in the aorto-caval region; IVC was compressed with abutment of 3rd part of duodenum. The patient was advised surgery. He underwent enbloc resection of the mass along with wedge resection of infiltrated duodenum.

Case 2: A 30-year-old lady presented with a progressively increasing huge abdominal mass of two to three months duration. She had been treated for malignant ovarian germ cell tumour – right oopherectomy followed by 4 cycles of systemic chemotherapy (BEP) four months ago, before she landed up to our centre with her last hope as she was declared “unresectable growing Teratoma “considering multi visceral involvements. She was explored at our centre and she underwent complete resection of the giant mass with multi-visceral resection. Post-resection, the mass weighed 17.2 kg, perhaps one of the largest reported Ovarian mass in literature.

Both the patients had unremarkable postoperative course and are well after one year of follow-up.

These two cases signify the importance of complete resection (with multi-visceral resection if required) of giant growing teratoma/somatic malignant transformation as surgery offers the only chance of cure, thereby survival. These sequelae of germ cell teratoma should not be declared ‘unresectable’ until they are explored in a high volume centre where the expert surgical and anaesthetic facilities are available


This site uses cookies. Some of these cookies are essential, while others help us improve your experience by providing insights into how the site is being used.

For more detailed information on the cookies we use, please check our Privacy Policy.

Customise settings