Oops, you're using an old version of your browser so some of the features on this page may not be displaying properly.

MINIMAL Requirements: Google Chrome 24+Mozilla Firefox 20+Internet Explorer 11Opera 15–18Apple Safari 7SeaMonkey 2.15-2.23

Poster presentation 1

1345 - Proposal of modification of UICC/AJCC staging system of gastric cancer including specific parameters for early gastric cancer


19 Dec 2015


Poster presentation 1


Simona Gurzu


Annals of Oncology (2015) 26 (suppl_9): 42-70. 10.1093/annonc/mdv523


S. Gurzu1, J. Orlowska2, H. Sugimura3, Z. Szentirmay4, I. Jung1

Author affiliations

  • 1 Pathology, University of Medicine and Pharmacy Targu-Mures, 540139 - Targu Mures/RO
  • 2 Pathology, MSC Memorial Cancer Centre and Institute Maria Sklodowska-Curie, 540139 - Warsaw/PL
  • 3 Pathology, Hamamatsu Oncology Center, 540139 - Hamamatsu/JP
  • 4 Pathology, National Institute of Oncology, 540139 - Budapest/HU


Abstract 1345


The aim of this paper was to propose an early gastric cancer (EGC) adapted staging system, based on an international consensus established between pathologists from Eastern Europe and Japan.


From 338 consecutive cases of gastric cancer (GC) diagnosed in four countries (Romania, Hungary, Poland, Japan), 29 cases were EGCs and were selected for further examinations. Based on their particular features, data from literature, and daily experience of the five Professors of Pathology, we suggest criteria for a specific staging system for EGC.


Because EGC can present aggressive behavior depending on the depth of invasion in the mucosa (upper-, middle-, and lower mucosa) and submucosa, the stages T1a and T1b should be subdivided. The pN parameter (lymph node metastases from EGC) should be reported based on the number of metastatic lymph nodes but the type of metastasis should also be mentioned (isolated cells, micrometastasis, metastasis). Angiolymphatic invasion and carcinomatosis of the lymph vessels should be included as distinct parameters of EGC, with prognostic and predictive role. The pM parameter (distant metastases from EGC) should be sub-divided in metastasis in distant lymph nodes (including skip metastasis), metastasis in one organ (liver, lung, brain, solitary bone metastasis, etc.), and metastasis in more than one organ (that includes multicentric bone metastasis).


Increasing number of GCs diagnosed in early stages and number of medical centers where endoscopic dissection of EGC is a routine technique, indicate the necessity of adapting AJCC/UICC staging system for EGC, correlating the Western and Eastern opinion. The research was founded by project UMFTGM-PO-CC-02-F01-19/2014.

Clinical trial identification


All authors have declared no conflicts of interest.

This site uses cookies. Some of these cookies are essential, while others help us improve your experience by providing insights into how the site is being used.

For more detailed information on the cookies we use, please check our Privacy Policy.

Customise settings