ESMO Advanced Course on NTRK Gene Fusion Barcelona October 2019

21 - 22 Oct 2019

Barcelona, Spain

Advanced Course on NTRK Gene Fusion 1000x1000

Presentations from all ESMO Advanced Courses are open to all according to the presenters' agreement to release them. ESMO thanks the authors for their generosity.

The use of these presentations is for personal educational purposes only.

Learning Objectives
  • Advanced Course on NTRK Gene Fusion 1000x1000
    Acquire knowledge of the TRK family members and their roles in ontogenesis
  • Understand the mechanisms of gene fusion and the different fusion partners involved
  • Learn how TRK receptors are structured and how their activation impacts signal transduction
  • Review the epidemiology of NTRK gene fusion in human tumours
  • Understand the methodology to identify NTRK gene fusion and the challenges of testing
  • Update knowledge on the present outcome obtained with NTRK inhibitors, their toxicities and clinical management

This event has been supported by an unrestricted educational grant from Bayer.

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