Peripheral parenteral nutrition is one of the easiest ways to provide nutrition for patients who have difficulty with enteral nutrition. But, on the other hand it is attended with danger such as, phlebitis. The purpose of this study was to investigate incidence of phlebitis and its risk factors in patients with peripheral parenteral nutrition administration.
Prospective observational study was performed with 289 hospitalized adult patients with gastrointestinal diseases. The researchers evaluated peripheral venous catheter that administered peripheral parenteral nutrition until their removal and investigated the incidence of phlebitis using phlebitis scale of Infusion Nurses Society (2016). Logistic regression model was used to identify risk factors involved with occurrence of phlebitis. The statistical significance limits were set at p < 0.05.
The incidence of phlebitis was 37.0% (107 cases). Among them, Grade I was 24.6% (71 cases), Grade II was 12.4% (36 cases) and Grade III and IV did not occur. Platelet count (OR 2.13, CI 1.07-4.26, p=.032), nutrition infusion rate (OR 0.36, CI 0.16-0.79, p=.012) and infusion period (OR 1.02, CI 1.00-1.03, p=.033) had statistically significance with phlebitis occurrence.
Using peripheral parenteral nutrition must be carefully reconsidered for patients with risk factors of phlebitis. In using peripheral parenteral nutrition, adjusting infusion rate deserves to be considered with care. Moreover, in case of extension of peripheral parenteral nutrition therapy, medical team must regards using another way such as middle line or central line for nutrition therapy in a serious light.
Clinical trial identification
Legal entity responsible for the study
Asan Medical Center.
Has not received any funding.
All authors have declared no conflicts of interest.