Oops, you're using an old version of your browser so some of the features on this page may not be displaying properly.

MINIMAL Requirements: Google Chrome 24+Mozilla Firefox 20+Internet Explorer 11Opera 15–18Apple Safari 7SeaMonkey 2.15-2.23

EONS Poster diplay

4053 - EONS Poster - Evaluation of support and information needs for patients with cancer in a Phase I trials unit.


22 Oct 2018


EONS Poster diplay


Patient Education and Advocacy

Tumour Site


Sarah Stapleton


Annals of Oncology (2018) 29 (suppl_8): viii689-viii693. 10.1093/annonc/mdy341


S. Stapleton1, L. O'Leary2, M. van Zyl3, J. Hanwell4, T. Wiseman5

Author affiliations

  • 1 Drug Development Unit, Royal Marsden Hospital NHS Foundation Trust, SW3 6JJ - London/GB
  • 2 Drug Development Unit, Royal Marsden Hospital NHS Foundation Trust, SM2 5PT - London/GB
  • 3 Drug Development Unit, Royal Marsden Hospital NHS Foundation Trust, london/GB
  • 4 Drug Development Unit, Royal Marsden Hospital NHS Foundation Trust, London/GB
  • 5 Applied Health Services Research, The Royal Marsden NHS Foundation Trust, Sw36JJ - London/GB


Login to access the resources on OncologyPRO.

If you do not have an ESMO account, please create one for free.

Abstract 4053


Advances in the understanding of the biological basis of cancer have resulted in a paradigm shift in drug development. Phase I trials with translational elements are conducted in clinical trials units for patients with cancer. The objective of this study was to evaluate any unmet needs of support and information for patients on Phase I trials. The aim was to utilise patient exerience to assess the need to change or develop delivery of information and support.


A qualitative approach was used. Patients and relatives of patients with cancer on Phase I trials formed two focus group. Group 1 consisted of 8 participants and group 2 10 participants, both lasted one hour. A semi structured schedule was used to prompt discussion, the focus groups were audio-recorded and transcribed verbatim. The data were organised using the Nvivo software package and analysed using Braun and Clarke's thematic analysis framework.


Four themes emerged from the data 1) face to face support; there was a general consensus that the best way to recieve information about treatment and disease was face to face. The relationships with the clinical staff were strong and important to maintain. At times when the trials unit was not accessible patients felt vulnerable 2) remote support; email was felt to be a good way to communicate information regarding appointments, the telephone clinic was useful for contact regarding sympton issues. Digital methods of information and support were potentially useful but needed to be thought through properly 3) getting the right information, at the right time , in the right way; patients felt that they needed extra information particularly in terms of feedback regarding the trials and signposting to support services 4) Relationships with other patients; this theme was about the benefit and value patients had in supporting each other within the treatment areas, however this was conflicted and may require extra support at times as there was a negative impact when fellow patients became unwell or died.


Based on the results from the analysis written patient information was redesigned. A quarterly forum is in development where patients can meet recieve well being advice and also feedback regarding the trials they are participating in.

Clinical trial identification

Legal entity responsible for the study

Royal Marsden NHS Foundation Trust.


Has not received any funding.

Editorial Acknowledgement


All authors have declared no conflicts of interest.

This site uses cookies. Some of these cookies are essential, while others help us improve your experience by providing insights into how the site is being used.

For more detailed information on the cookies we use, please check our Privacy Policy.

Customise settings
  • Necessary cookies enable core functionality. The website cannot function properly without these cookies, and you can only disable them by changing your browser preferences.